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Q3657834
Português
Texto associado
A Adoção de Animais é um Ato de Amor e
Responsabilidade
A adoção de animais é um ato de amor e
responsabilidade que pode mudar a vida dos animais e
de suas famílias adotivas. Ao adotar, você oferece uma
nova chance de vida feliz e saudável e ajuda a reduzir o
número de abandonados nas ruas e abrigos.
Existem muitos animais que precisam de um lar amoroso
e seguro. Ao adotar de um abrigo ou organização de
resgate, você dá a oportunidade de encontrar um lar
permanente e receber os cuidados necessários.
Adotar um animal é uma responsabilidade a longo prazo.
É preciso avaliar se você tem tempo e recursos para
garantir exercício, alimentação saudável, cuidados
veterinários e atenção constante.
Em resumo, a adoção de animais contribui para reduzir
abandonos e maus-tratos, oferecendo a eles uma nova
chance de vida. Se decidir adotar, certifique-se de ter
condições para cuidar adequadamente e procure abrigos
e organizações de resgate locais.
Associação de Proteção aos Animais de Carlos
Barbosa/RS
Texto Adaptado
https://www.abapa.ong.br/a-adocao-de-animais-e-um-ato-de-amor-e-re
sponsabilidade
No trecho "...oferecendo a eles uma nova chance de
vida", observa-se o emprego do verbo "oferecer" em sua
forma de gerúndio. Considerando as regras da regência
verbal, assinale a alternativa correta.
Q3657833
Português
Texto associado
A Adoção de Animais é um Ato de Amor e
Responsabilidade
A adoção de animais é um ato de amor e
responsabilidade que pode mudar a vida dos animais e
de suas famílias adotivas. Ao adotar, você oferece uma
nova chance de vida feliz e saudável e ajuda a reduzir o
número de abandonados nas ruas e abrigos.
Existem muitos animais que precisam de um lar amoroso
e seguro. Ao adotar de um abrigo ou organização de
resgate, você dá a oportunidade de encontrar um lar
permanente e receber os cuidados necessários.
Adotar um animal é uma responsabilidade a longo prazo.
É preciso avaliar se você tem tempo e recursos para
garantir exercício, alimentação saudável, cuidados
veterinários e atenção constante.
Em resumo, a adoção de animais contribui para reduzir
abandonos e maus-tratos, oferecendo a eles uma nova
chance de vida. Se decidir adotar, certifique-se de ter
condições para cuidar adequadamente e procure abrigos
e organizações de resgate locais.
Associação de Proteção aos Animais de Carlos
Barbosa/RS
Texto Adaptado
https://www.abapa.ong.br/a-adocao-de-animais-e-um-ato-de-amor-e-re
sponsabilidade
No trecho "Se decidir adotar, certifique-se de ter
condições para cuidar adequadamente e procure abrigos
e organizações de resgate locais", o vocábulo "se"
aparece em duas ocorrências com valores distintos.
Assinale a alternativa correta quanto à sua classificação.
Q3657832
Português
Texto associado
A Adoção de Animais é um Ato de Amor e
Responsabilidade
A adoção de animais é um ato de amor e
responsabilidade que pode mudar a vida dos animais e
de suas famílias adotivas. Ao adotar, você oferece uma
nova chance de vida feliz e saudável e ajuda a reduzir o
número de abandonados nas ruas e abrigos.
Existem muitos animais que precisam de um lar amoroso
e seguro. Ao adotar de um abrigo ou organização de
resgate, você dá a oportunidade de encontrar um lar
permanente e receber os cuidados necessários.
Adotar um animal é uma responsabilidade a longo prazo.
É preciso avaliar se você tem tempo e recursos para
garantir exercício, alimentação saudável, cuidados
veterinários e atenção constante.
Em resumo, a adoção de animais contribui para reduzir
abandonos e maus-tratos, oferecendo a eles uma nova
chance de vida. Se decidir adotar, certifique-se de ter
condições para cuidar adequadamente e procure abrigos
e organizações de resgate locais.
Associação de Proteção aos Animais de Carlos
Barbosa/RS
Texto Adaptado
https://www.abapa.ong.br/a-adocao-de-animais-e-um-ato-de-amor-e-re
sponsabilidade
O texto "A adoção de animais é um ato de amor e
responsabilidade" apresenta uma argumentação em
defesa da adoção responsável de animais,
estruturando-se em torno de valores éticos, sociais e
pragmáticos. Considerando a compreensão textual e o
significado contextual de expressões, assinale a
alternativa correta.
Q3657831
Português
Texto associado
A Adoção de Animais é um Ato de Amor e
Responsabilidade
A adoção de animais é um ato de amor e
responsabilidade que pode mudar a vida dos animais e
de suas famílias adotivas. Ao adotar, você oferece uma
nova chance de vida feliz e saudável e ajuda a reduzir o
número de abandonados nas ruas e abrigos.
Existem muitos animais que precisam de um lar amoroso
e seguro. Ao adotar de um abrigo ou organização de
resgate, você dá a oportunidade de encontrar um lar
permanente e receber os cuidados necessários.
Adotar um animal é uma responsabilidade a longo prazo.
É preciso avaliar se você tem tempo e recursos para
garantir exercício, alimentação saudável, cuidados
veterinários e atenção constante.
Em resumo, a adoção de animais contribui para reduzir
abandonos e maus-tratos, oferecendo a eles uma nova
chance de vida. Se decidir adotar, certifique-se de ter
condições para cuidar adequadamente e procure abrigos
e organizações de resgate locais.
Associação de Proteção aos Animais de Carlos
Barbosa/RS
Texto Adaptado
https://www.abapa.ong.br/a-adocao-de-animais-e-um-ato-de-amor-e-re
sponsabilidade
Analise o período retirado do texto:
"Existem muitos animais que precisam de um lar amoroso e seguro."
Considerando as regras de concordância verbal, assinale a alternativa correta
"Existem muitos animais que precisam de um lar amoroso e seguro."
Considerando as regras de concordância verbal, assinale a alternativa correta
Q3657830
Português
Texto associado
A Adoção de Animais é um Ato de Amor e
Responsabilidade
A adoção de animais é um ato de amor e
responsabilidade que pode mudar a vida dos animais e
de suas famílias adotivas. Ao adotar, você oferece uma
nova chance de vida feliz e saudável e ajuda a reduzir o
número de abandonados nas ruas e abrigos.
Existem muitos animais que precisam de um lar amoroso
e seguro. Ao adotar de um abrigo ou organização de
resgate, você dá a oportunidade de encontrar um lar
permanente e receber os cuidados necessários.
Adotar um animal é uma responsabilidade a longo prazo.
É preciso avaliar se você tem tempo e recursos para
garantir exercício, alimentação saudável, cuidados
veterinários e atenção constante.
Em resumo, a adoção de animais contribui para reduzir
abandonos e maus-tratos, oferecendo a eles uma nova
chance de vida. Se decidir adotar, certifique-se de ter
condições para cuidar adequadamente e procure abrigos
e organizações de resgate locais.
Associação de Proteção aos Animais de Carlos
Barbosa/RS
Texto Adaptado
https://www.abapa.ong.br/a-adocao-de-animais-e-um-ato-de-amor-e-re
sponsabilidade
No período "Ao adotar de um abrigo ou organização de
resgate, você dá a oportunidade de encontrar um lar
permanente e receber os cuidados necessários", o uso
da vírgula se justifica porque:
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650844
Inglês
The act of reading is not a passive activity of decoding
words, but rather an interactive process that requires
interpretation, contextualization, and critical reflection. In
academic environments, the relationship between
reading and text production becomes central, since one
influences and enriches the other. Based on this
perspective, which of the following statements represents
this relationship?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650843
Pedagogia
In a pedagogical meeting, a professor emphasized the
importance of integrating oral and written practices in
education. Which statement best reflects this idea?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650842
Inglês
Word formation is a central topic in linguistics, particularly
within the field of morphology. It refers to the
mechanisms through which new words are created or
existing words are modified in a language. These
processes play a crucial role in language evolution,
lexical expansion, and communicative efficiency. English,
as a dynamic and flexible language, presents a variety of
word formation strategies. Judge the sentences below as
TRUE (T) or FALSE (F).
(__) Derivation is the process of creating new words by adding prefixes or suffixes to a base word. For example, the addition of the prefix un- in unhappy changes the meaning, while the suffix -ness in happiness transforms an adjective into a noun. Derivation is highly productive and contributes significantly to vocabulary growth.
(__) Compounding involves combining two or more free morphemes to form a single lexical item, such as toothbrush, blackboard, or website. This process allows for the creation of more specific or complex meanings by linking existing words.
(__) Conversion occurs when a word changes its grammatical category without any alteration in form. For example, the noun email can be used as the verb to email, or the verb to run can function as the noun a run. This strategy highlights the flexibility of English word classes.
The CORRECT sequence is:
(__) Derivation is the process of creating new words by adding prefixes or suffixes to a base word. For example, the addition of the prefix un- in unhappy changes the meaning, while the suffix -ness in happiness transforms an adjective into a noun. Derivation is highly productive and contributes significantly to vocabulary growth.
(__) Compounding involves combining two or more free morphemes to form a single lexical item, such as toothbrush, blackboard, or website. This process allows for the creation of more specific or complex meanings by linking existing words.
(__) Conversion occurs when a word changes its grammatical category without any alteration in form. For example, the noun email can be used as the verb to email, or the verb to run can function as the noun a run. This strategy highlights the flexibility of English word classes.
The CORRECT sequence is:
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650841
Inglês
In English, some words used in everyday communication
are not entirely new creations, but rather shortened
versions of longer forms that remain widely understood
and accepted. These shortened words often become
more common than their original forms, especially in
informal contexts. Considering the options below, identify
which one illustrates this phenomenon:
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650840
Inglês
In the teaching of English as a foreign language, the
development of reading skills goes beyond the
recognition of vocabulary and grammatical structures. It
involves strategies that promote comprehension,
inference, and critical analysis of texts. Considering
contemporary approaches to English teaching, which of
the following alternatives reflects the role of reading in
language learning?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650839
Inglês
During a grammar exam, students were asked to identify
the option that represents a nominal phrase rather than a
verbal one. Which option is correct?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650838
Inglês
Consider the sentence below:
"Her actual plan was to pretend she was studying with her parents at the library, but they didn't realize the truth."
How many false friends are there?
"Her actual plan was to pretend she was studying with her parents at the library, but they didn't realize the truth."
How many false friends are there?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650837
Inglês
During a training session on text genres, teachers were
asked to point out an example that clearly represents a
written academic text genre commonly used in education.
Which option is correct?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650836
Inglês
Complete the sentence with the appropriate prepositions:
She is interested ___ learning new languages, focused ___ improving her pronunciation, and proud ___ her progress so far.
Select the correct option.
She is interested ___ learning new languages, focused ___ improving her pronunciation, and proud ___ her progress so far.
Select the correct option.
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650835
Inglês
In a classroom discussion about different types of nouns,
the teacher asked students to identify which group
contains only abstract nouns. Which option should they
choose?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650834
Inglês
In academic English, phrasal verbs often carry meanings
that go beyond the literal combination of verb and
preposition, demanding contextual interpretation.
Observe the sentence below:
"Despite the unexpected technical problems during the presentation, the team managed to ___ the challenges and deliver the project on time."
Which option correctly completes the sentence with the most appropriate phrasal verb?
Observe the sentence below:
"Despite the unexpected technical problems during the presentation, the team managed to ___ the challenges and deliver the project on time."
Which option correctly completes the sentence with the most appropriate phrasal verb?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650833
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
Which connector in the sentence "The research could
improve diagnosis and, ultimately, treatments for
endometriosis" indicates a relation of finality/goal?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650832
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
Considering the final section of the text, where Giudice
states "We're finally getting closer to faster diagnosis
and, eventually, tailored treatment for the millions of
women who suffer from endometriosis", what does this
conclusion primarily contribute to the text's coherence?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650831
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
In the paragraph beginning with "This data is messy; it
was not collected for research purposes but for the real,
human purpose of helping women who need care", which
cohesive device connects the idea of limitation with
contrast?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650830
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
Which sentence correctly identifies the verb tense in the
clause "We hope this can spur a sea change in how we
approach this disorder"?
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