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Questões de Concurso Sobre voz ativa e passiva | passive and active voice em inglês

Questões Discursivas

Foram encontradas 367 questões

Q2459378 Inglês

Read Text I and answer the fourteen questions that follow it

                           

 Text I The “literacy turn” in education: reexamining 

what it means to be literate


In response to the phenomena of mass migration and the emergence of digital communications media that defined the last decade of the 20th century, the New London Group (NLG) called for a broader view of literacy and literacy teaching in its 1996 manifesto, A Pedagogy of Multiliteracies: Designing Social Futures. The group argued that literacy pedagogy in education must (1) reflect the increasing cultural and linguistic diversity of the contemporary globalized world, and (2) account for the new kinds of texts and textual engagement that have emerged in the wake of new information and multimedia technologies. In order to better capture the plurality of discourses, languages, and media, they proposed the term ‘multiliteracies’.

Within the NLG’s pedagogy of multiliteracies, language and other modes of communication are viewed as dynamic resources for meaning making that undergo constant changes in the dynamics of language use as learners attempt to achieve their own purposes. Within this broader view of literacy and literacy teaching, learners are no longer “users as decoders of language” but rather “designers of meaning.” Meaning is not viewed as something that resides in texts; rather, deriving meaning is considered an active and dynamic process in which learners combine and creatively apply both linguistic and other semiotic resources (e.g., visual, gesture, sound, etc.) with an awareness of “the sets of conventions connected with semiotic activity [...] in a given social space” (NLG, 1996, p. 74).

Grounded within the view that learning develops in social, cultural, and material contexts as a result of collaborative interactions, NLG argued that instantiating literacy-based teaching in classrooms calls on the complex integration and interaction of four pedagogical components that are neither hierarchical nor linear and can at times overlap: situated practice, overt instruction, critical framing, and transformed practice. […]

Although the NLG’s pedagogy of multiliteracies was conceived as a “statement of general principle” (1996, p. 89) for schools, the group’s call for educators to recognize the diversity and social situatedness of literacy has had a lasting impact on foreign language (FL) teaching and learning. The reception of the group’s work along with that of other scholars from critical pedagogy appeared at a time when the field was becoming less solidly anchored in theories of L2 acquisition and more interested in the social practice of FL education itself. In the section that follows, we describe the current state of FL literacy studies as it has developed in recent years, before finally turning to some very recent emerging trends that we are likely to see develop going forward.

(Adapted from: https://www.colorado.edu/center/altec/sites/default/files/ attachedfiles/moving_toward_multiliteracies_in_foreign_language_teaching.pdf)

The verb form in “the NLG’s pedagogy of multiliteracies was conceived” (4th paragraph) is in the
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Q2392970 Inglês
Text 1



From Shakespeare to Harry Styles: Have audiences always been rowdy?


By Clare Thorp12th July 2023



From Pink being given a giant wheel of Brie to Harry Syles getting pelled in the face by a mystery object, disruptive music and theatre shows seems to be on the rise. But is it anything new, asks Clare Thorp.



When Harry Styles was pelted with chicken nuggets while on stage at New York's Madison Square Gardens last summer, he took it in his stride. "Interesting approach," smiled Styles, who has also weathered kiwi fruits, Skittles and bunches of flowers while performing. But when a mystery object hit him in the eye at a concert in Vienna last weekend, he wasn't laughing but, rather, wincing in pain.


It was the latest in a string of incidents where audience members have hurled potentially dangerous objects at performers. Earlier this month Drake was hit on the arm by a flying phone. That came days after country singer Kelsea Ballerini was struck in the face with a bracelet. In May, Bebe Rexha was taken to hospital and needed multiple stitches after a phone hit her in the eye. A man, since charged with assault, told police he thought it "would be funny" to try and hit the singer.


It's not just live music seeing disruptive behaviour. In April, police were called to a performance of The Bodyguard musical in Manchester when rowdy audience members reacted with "unprecedented levels of violence" to staff. At other venues there has been everything from "heated arguments" to full-on brawls. And in the US, one fan's disruption of a Broadway play in December 2022 followed several other incidents of audience outbursts.


Across the cultural sphere, it feels like audiences are misbehaving. At a recent Las Vegas show, Adele weighed in, saying: "Have you noticed how people are like, forgetting … show etiquette at the moment? People just throwing shit on stage" – before warning fans not to try it with her.


Billie Eilish meanwhile, says this kind of thing, while "infuriating", is nothing new. "I've been getting hit on stage with things for like, literally, six years," she told the Hollywood Reporter. Dr Kirsty Sedgman, a senior lecturer in theatre at the University of Bristol who specialises in audience research, also cautions against calling it a new trend. "People have always thrown things on stage," says Sedgman, whose latest book, On Being Unreasonable, explores widening divisions in society over how we use public space. "Whether that's fruit as a way to signify displeasure, or softer items like underwear and flowers as a signal of adoration." Back In 1775, a performer in Sheridan's The Rivals stopped the show when he was pelted with an apple.



Adapted from: https://www.bbc.com/culture/article/20230712
The objective of question 3 is to explore the following aspect of the passive voice theory:
Alternativas
Q2392969 Inglês
Text 1



From Shakespeare to Harry Styles: Have audiences always been rowdy?


By Clare Thorp12th July 2023



From Pink being given a giant wheel of Brie to Harry Syles getting pelled in the face by a mystery object, disruptive music and theatre shows seems to be on the rise. But is it anything new, asks Clare Thorp.



When Harry Styles was pelted with chicken nuggets while on stage at New York's Madison Square Gardens last summer, he took it in his stride. "Interesting approach," smiled Styles, who has also weathered kiwi fruits, Skittles and bunches of flowers while performing. But when a mystery object hit him in the eye at a concert in Vienna last weekend, he wasn't laughing but, rather, wincing in pain.


It was the latest in a string of incidents where audience members have hurled potentially dangerous objects at performers. Earlier this month Drake was hit on the arm by a flying phone. That came days after country singer Kelsea Ballerini was struck in the face with a bracelet. In May, Bebe Rexha was taken to hospital and needed multiple stitches after a phone hit her in the eye. A man, since charged with assault, told police he thought it "would be funny" to try and hit the singer.


It's not just live music seeing disruptive behaviour. In April, police were called to a performance of The Bodyguard musical in Manchester when rowdy audience members reacted with "unprecedented levels of violence" to staff. At other venues there has been everything from "heated arguments" to full-on brawls. And in the US, one fan's disruption of a Broadway play in December 2022 followed several other incidents of audience outbursts.


Across the cultural sphere, it feels like audiences are misbehaving. At a recent Las Vegas show, Adele weighed in, saying: "Have you noticed how people are like, forgetting … show etiquette at the moment? People just throwing shit on stage" – before warning fans not to try it with her.


Billie Eilish meanwhile, says this kind of thing, while "infuriating", is nothing new. "I've been getting hit on stage with things for like, literally, six years," she told the Hollywood Reporter. Dr Kirsty Sedgman, a senior lecturer in theatre at the University of Bristol who specialises in audience research, also cautions against calling it a new trend. "People have always thrown things on stage," says Sedgman, whose latest book, On Being Unreasonable, explores widening divisions in society over how we use public space. "Whether that's fruit as a way to signify displeasure, or softer items like underwear and flowers as a signal of adoration." Back In 1775, a performer in Sheridan's The Rivals stopped the show when he was pelted with an apple.



Adapted from: https://www.bbc.com/culture/article/20230712
Passive voice is commonly used in journalistic texts. The extract below was retrieved from text 1. It justifies the use of passive voice because:

       From Pink being given a giant wheel of Brie to Harry Syles getting pelled in the face by a mystery object, disruptive music and theatre shows seems to be on the rise. 
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Q2392602 Inglês
Text 05 - Syllabus - See an explanation of the term ‘Syllabus’.



A syllabus is a document that describes what the contents of a language course will be and the order in which they will be taught. The content of a syllabus normally reflects certain beliefs about language and language learning.


Example

A syllabus might be designed around the order in which grammatical items are introduced. Starting with 'present simple' then 'past simple', then 'present perfect' etc.


In the classroom

There are many different types of syllabus (although often in language classrooms the syllabus from the course book is the only document). Syllabus types include grammatical, lexical and functional, which focus on the building blocks of language, and task-based and learner-centred, which focus on processes of communication and learning. 



Adapted from: https://www.teachingenglish.org.uk/professional-development/teachers/knowing-subject/q-s/syllabus accessed on July 18th, 2023.

There are three selections in Text 05 that appear underlined. All of them bring sentences...
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Q2382892 Inglês

Text 22A4-II 


      Over the past few years, Peruvian authorities have tried to find ways to manage increasing visitor numbers to the popular site which often had long lines and overcrowding, leaving many tourists unable to enter. Machu Picchu was awarded UNESCO World Heritage status in 1983 and is described by the awarding body as probably the most amazing urban creation of the Inca Empire at its height. It added its giant walls, terraces, and ramps “seem as if they have been cut naturally” into the continuous rock escarpments. The citadel, 130 km from Cusco, was built in the 15th as a religious sanctuary for the Incas at an altitude of 2,490 meters. 


      However, UNESCO also highlighted the challenges faced by the site, which it says requires more stringent management. “Tourism itself represents a double-edged sword by providing economic benefits but also by resulting in major cultural and ecological impacts,” said UNESCO. “The strongly increasing number of visitors to the historic sanctuary of Machu Picchu must be matched by an adequate management regulating access, diversifying the offer, and efforts to fully understand and minimize impacts. A larger appropriate and increasing share of the significant tourism revenues could be reinvested in planning and management.”. 


Internet: <https://www.thenationalnews.com> (adapted).

Each of the following options presents a reformulation of the last sentence of text 22A4-II, which was originally written in the Passive Voice. Choose the one that maintains its meaning and correction. 
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Q2357615 Inglês
The passive voice in line 08 ‘Other names were considered,’ has the ‘passive agent’ that will become the subject in active voice described in alternative: 
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Q4162853 Inglês

Dutch government bans phones in schools The Dutch government has announced a ban ______01 mobile phones, tablets, and smartwatches in classrooms starting ______02 January 1, 2024.


The aim is to reduce distractions ______03 lessons and promote better concentration and studying opportunities for students. ______04, devices

 

_______________05 if they are specifically required for digital skills lessons, for medical reasons, or students with disabilities.


Education Minister Robbert Dijkgraaf ______06 that ______07 mobile phones are a significant part of ______08 lives, they are not suitable for the classroom, and scientific research ______09 this view.


The ban is the result of an agreement between the ministry, schools, and related organizations. Schools have the flexibility to implement the ban in their way, but if the desired outcomes ______10 achieved by the summer of 2024, legal rules ______11 enforced.



Source: https://www.newsinlevels.com/products/dutch government-bans-phones-in-schools-level-3/. 

The blank numbered as “10” could be CORRECTLY filled with:
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Q4162845 Inglês

Dutch government bans phones in schools The Dutch government has announced a ban ______01 mobile phones, tablets, and smartwatches in classrooms starting ______02 January 1, 2024.


The aim is to reduce distractions ______03 lessons and promote better concentration and studying opportunities for students. ______04, devices

 

_______________05 if they are specifically required for digital skills lessons, for medical reasons, or students with disabilities.


Education Minister Robbert Dijkgraaf ______06 that ______07 mobile phones are a significant part of ______08 lives, they are not suitable for the classroom, and scientific research ______09 this view.


The ban is the result of an agreement between the ministry, schools, and related organizations. Schools have the flexibility to implement the ban in their way, but if the desired outcomes ______10 achieved by the summer of 2024, legal rules ______11 enforced.



Source: https://www.newsinlevels.com/products/dutch government-bans-phones-in-schools-level-3/. 

The blank numbered as “5” could be CORRECTLY filled with: 
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Q3698430 Inglês

Birthday’s origin


In ancient Rome, there was the habit of celebrating the birthday of a person. There weren’t parties like we know today, but cakes were prepared and offers were made. Then, the habits of wishing happy birthday, giving gifts and lighting candles became popular as a way to protect the birthday person from devils and ensure good things to the next year in the person’s life. The celebrations only became popular like we know today after fourteen centuries, in a collective festival performed in Germany.


Fonte:

https://www.wizard.com.br/idiomas/textos-

sem-ingles-para-iniciantes/



In the sentence “There weren’t parties like we know today, but cakes were prepared and offers ___________.”, the appropriate verb form for the ellipsis is




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Q3668613 Inglês
Colombia deadliest country for environmentalists - report

By Vanessa Buschschlüter
BBC News
Tuesday, September 13, 2023

At least 177 environmental activists were killed across the world last year, a report by the non-governmental organisation Global Witness suggests.
Sixty of the killings took place in Colombia, making it the deadliest country for environmental defenders.
Global Witness says very few of the perpetrators of the killings are ever brought to justice.
The group said in its report that the total number of those killed in the country since it began recording data on attacks on environmentalists in 2012 had amounted to at least 382.
While that makes it the country with the highest number of murders of green activists anywhere in the world, other countries in Latin America also proved deadly.
Brazil recorded 34 murders of defenders of the environment. Mexico 31 and Honduras 11. The Amazon region saw 39 killings, with many of the victims from indigenous communities.
"Research has shown again and again that Indigenous peoples are the best guardians of the forests and therefore play a fundamental role in mitigating the climate crisis," said Global Witness senior adviser Laura Furones.
Global witness said the full scale of the killings was unknown, with a lack of independent monitoring and restrictions on free press in many countries leading to an underreporting of cases.
They have called on governments around the world to urgently address the issue, adding that defenders were also increasingly being subjected to legal efforts to silence them.

(Adapted from washingtonpost.com)
Regarding Colombia deadliest country for environmentalists - report text which of the following sentences uses the passive form in its structure?
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Q3654169 Inglês
Identify the verb tense in the following sentence. The book was written in China.
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Q3637152 Inglês

Read the text and answer the following questions


American man stolen as a baby in Chile meets mother at 42


By CNN's Rafael Romo


Published 3:05 AM EDT, Sat September 9, 2023


Jimmy Lippert Thyden says he always knew he was adopted. He also knew that he had been born not in the United States, but in Chile. Raised in Virginia by very loving and committed adoptive parents, he says he never lacked anything. The 42-year-old who served in the US Marines is now an attorney who is married and has two young daughters.


“I was told that I was given up for adoption out of love,” Thyden said. “Given by a mother who loved me and wanted the best for me: a life full of opportunity, education and meaning.”


That all started to change in 2012 when his adoptive mother gave him his adoption paperwork as he was preparing to deploy to Afghanistan. Thyden says that when he started looking closely at the adoption files, he found out that there were many discrepancies and inconsistencies.


There was one document that said he had no known father or mother. Another provided the name of a biological mother and her address. A third document specified the baby had no living relatives, and a fourth stated that he had been given up for adoption days after birth. Yet another document said he had been given up for adoption when he was two years old.


Thyden says it was not until a few months ago, when his wife read about the case of Scott Lieberman, that he became actively engaged in uncovering the truth about his adoption.


As CNN reported in May, Lieberman, the 42-yearold American from San Francisco, had also been adopted from Chile and had recently found out that he had been stolen as a baby. That’s how Thyden learned about “Nos Buscamos” (We Search for Each Other), a Chilean non-profit organization devoted to helping people stolen as babies find their biological parents and families. 


During the dictatorship of General Augusto Pinochet, from 1973 to 1990, many babies were funneled to adoption agencies. Some of the children came from rich families, who in many cases gave up babies born out of wedlock. Other babies from poorer backgrounds were simply stolen.


Chilean officials say the number of stolen babies could be in the thousands, but the country’s investigation into the controversial adoptions has languished. Some who took part in the illegal adoptions have died. Many clinics or hospitals where the babies were allegedly stolen no longer exist.


After reaching out to “Nos Buscamos,” Thyden says he got an email the next day from its director, Constanza del Río, who told him to call her right away. With the help of MyHeritage, an online genealogy company, Thyden got a match within a few weeks. When the match came back, del Río says she knew the next step was making a phone call to María Angélica González, 69, a woman who had believed for decades her son had died shortly after being born.


“She could not believe it. She thought it was a joke in poor taste because she had been told her premature baby boy had died,” del Río said. Del Río says González had been told the baby’s body had been disposed of in the trash. During the Pinochet dictatorship, when several thousand people were killed and disappeared, asking too many questions or protesting in a loud way could be dangerous. (Chile will mark the 50th anniversary of the coup that brought Pinochet to power on September 11.)


Learning the truth has been bittersweet for Thyden. He’s happy to finally know his true origins but sad about what his biological mother went through.


After three agonizing months, he was finally able to travel to Chile to give his biological mother the hug that had to wait for 42 years. When they met in the southern city of Valdivia in mid-August, he was finally able to utter the words he had been rehearsing for weeks. “Hola, mamá!,” he said when they finally embraced.


Thyden says that learning the truth has also been painful because his adoptive parents were also lied to and victimized. He says his adoptive parents first contacted an adoption agency in Virginia and specifically asked to adopt a child the right way, through a reputable agency, something that they put in writing.


“It’s not wasted on me that I recognize that I’m blessed in the fact that I have loving families on both sides of the equator. Are those things that I did because of where I was or are those things that I did because they are at the core of who I am?,” said Thyden, who pointed out that he says “mom” or “mother” when he’s speaking about his American adoptive mother and “mamá” when he refers to his Chilean, biological mother.


In the end, he says, the wisdom about what happened to him came from his five-year-old daughter, who told him if a bad thing hadn’t happened, she wouldn’t be here. And her father, she told him, has not one but two families who love him deeply.



(Adapted from www.cnn.com)

Regarding American man stolen as a baby in Chile meets mother at 42 text, read the following sentences and select the one that uses the passive form in its structure.



I - Jimmy Lippert Thyden says he always knew he was adopted.


II - The 42-year-old who served in the US Marines is now an attorney who is married and has two young daughters.


III - I was told that I was given up for adoption out of love.


IV - He became actively engaged in uncovering the truth about his adoption.


V - During the dictatorship of General Augusto Pinochet, from 1973 to 1990, many babies were funneled to adoption agencies.


VI - Lieberman, the 42-year-old American from San Francisco, had also been adopted from Chile.



Mark the correct alternative: 

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Q3634351 Inglês

Answer questions according to TEXT.


texto_3.png (523×544)

Which sentence from Text Vis an example of passive voice? 
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Q3613187 Inglês
Qual das seguintes frases está na voz passiva?
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Q3587391 Inglês

About passive voice, analyze the sentences e choose the right option:



I- Sometimes, the agent isn’t necessary;


II- We can change the ‘verb to be’ by ‘got’, without change the meaning;


III- If we put the sentence ‘The Cartoon Introduction to Climate Change was first published in 2014’ in active voice the subject would be Yoram and Grady;

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Q3581499 Inglês
Another rare spotless giraffe found — the first ever seen in the wild





(Available at: https://www.nationalgeographic.com/animals/article/spotless-giraffe-found-in-the-wild-for-thefirst-time – text especially adapted for this test).
In the sentence “(…) another spotless giraffe calf has now been seen and photographed” (l. 01-02) there is a passive voice structure. Which of the options bellow shows the structure correctly rewritten in the active voice, in the same verb tense and with no significative changes in meaning?
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Q3560246 Inglês

Text 1


Green shoppers around the world


If you want to be a responsible consumer, think about not just how much you buy, but also about what’s good for the planet. Green Shoppers United is an international non-profit organization for the promotion of responsible consumerism.


Labels


Read the labels. Some...................the ingredients that manufacturers use in products, such as cosmetics or toiletries, can damage the environment. Some ingredients are only used...................make things prettier, or more colorful, but they might also be harmful. Don’t buy things that contain substances that harm you or the world you live................... For example, research shows a potential link...................the preservatives called parabens, often found in beauty products, and some types of cancer. 


Transport


In today’s global economy, it is easier for companies to buy products and materials where they’re cheap, and transport them over enormous distances to get them to customers. If you can, buy things locally. The local food movement has grown steadily in recent years, and it’s often possible to track down locally grown, or produced, products, rather than those that have been transported long distances. If we stop buying goods that have had to fly over continents to get to us, companies may stop transporting them around unnecessarily. A bargain may cost you less personally, but the real price we pay for it in the long run may turn out to be too high, as jet fuel continues to pollute our environment. 


Environment 


Responsible consumers recycle to reduce waste, and its negative impact on our environment. A lot of the plastic packaging we use for food and drink is recyclable, but not all of it. The most common packaging materials are still non-recyclable polyethylene and PVC. Seventy million tons are used every year. Look at the recycling labels carefully. Manufacturers should use recyclable plastics, like PET, wherever possible. Some have also begun using lighter materials, for example, 30% lighter PET plastic for drinks bottles, to reduce the amount of plastic waste. Transporting lighter materials is cheaper, and uses less fuel, too – so the solution may actually benefit everyone. 


Packaging


We’ve all purchased products wrapped in foil, then sealed in a bag, and then put in a box. Why? Write to companies that you think produce wasteful packaging. Ask them to think about what’s really necessary. Make them realize they can save money by using less packaging and, at the same time, help save our planet.


Consumers


A lot of us expect products these days to be more environmentally friendly. However, research has shown that we don’t want to pay more, and we don’t want to compromise on the quality of products, either. For example, one manufacturer recently had to switch back to less environmental packaging of potato chips, just because customers didn’t like the noise their “green” bags made when they were opened! Think about the effects of your shopping choices. Buy less to save the world, and join our effort to make shopping greener!




Study the underlined words in the following sentence.

“The local food movement has grown steadily in recent years, and it’s often possible to track down locally grown, or produced, products, rather than those that have been transported long distances.”

We can infer that the underlined words are being used in which verb tenses?
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Q3556087 Inglês
In the sentence "The book was read by John," which voice is being used?
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Q3542908 Inglês

Analyze the following expression and answer the question


Q33.png (251×182)

Fonte:https://www.amazon.com.br/Light-Has-Been-BrokenSupernatural-ebook/acesso em: 06 de out de 2023.

In the expression, “The light has been broken.” the highlighted verbs are respectively in the: 
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Q3456994 Inglês
Stanford Medicine scientists transform cancer cells into weapons against cancer

March 1, 2023 - By Christopher Vaughan


(1º§) Some cities fight gangs with ex-members who  educate kids and starve gangs of new recruits. Stanford Medicine researchers have done something similar with cancer — altering cancer cells so that they teach the body's immune system to fight the very cancer the cells came from.


(2º§) "This approach could open up an entirely new therapeutic approach to treating cancer," said Ravi Majeti, MD, PhD, a professor of hematology and the study's senior author. The research was published March 1 in Cancer Discovery. The lead author is Miles Linde, PhD, a former PhD student in immunology who is now at the Fred Hutchinson Cancer Institute in Seattle.


(3º§) Some of the most promising cancer treatments use the patient's own immune system to attack the cancer, often __ taking the brakes off immune responses to cancer or by teaching the immune system to recognize and attack the cancer more vigorously. T cells, part of the immune system that learns to identify and attack new pathogens such as viruses, can be trained to recognize specific cancer antigens, which are proteins that generate an immune response.


(4º§) For instance, in CAR T-cell therapy, T cells are taken from a patient, programmed to recognize a specific cancer antigen, then returned to the patient. But there are many cancer antigens, and physicians sometimes need to guess which ones will be most potent.


(5º§) A better approach would be to train T cells to recognize cancer via processes that more closely mimic the way things naturally occur in the body — like the way a vaccine teaches the immune system to recognize pathogens. T cells learn to recognize pathogens because special antigen presenting cells (APCs) gather pieces of the pathogen and show them to the T cells in a way that tells the T cells, "Here is what the pathogen looks like — go get it."


(6º§) Something similar in cancer would be for APCs to gather up the many antigens that characterize a cancer cell. That way, instead of T cells being programmed to attack one or a few antigens, they are trained to recognize many cancer antigens and are more likely to wage a multipronged attack on the cancer.


(7º§) Now that researchers have become adept at transforming one kind of cell into another, Majeti and his colleagues had a hunch that if they turned cancer cells into a type of APC called macrophages, they would be naturally adept at teaching T cells what to attack.


(8º§) "We hypothesized that maybe cancer cells reprogrammed into macrophage cells could stimulate T cells because those APCs carry all the antigens of the cancer cells they came from," said Majeti, who is also the RZ Cao Professor, assistant director of the Institute for Stem Cell Biology and Regenerative Medicine and director of the Ludwig Center for Cancer Stem Cell Research and Medicine.


(9º§) The study builds on prior research from the Majeti lab showing that cells taken from patients with a type of acute leukemia could be converted into non-leukemic macrophages with many of the properties of APCs.


(10º§) In the current study, the researchers programmed mouse leukemia cells so that some of them could be induced to transform themselves into APCs. When they tested their cancer vaccine strategy on the mouse immune system, the mice successfully cleared the cancer.


(11º§) "When we first saw the data showing clearance of the leukemia in the mice __ working immune systems, we were blown away," Majeti said. "We couldn't believe it worked as well as it did."


(12º§) Other experiments showed that the cells created from cancer cells were indeed acting as antigen-presenting cells that sensitized T cells to the cancer. "What's more, we showed that the immune system remembered what these cells taught them," Majeti said. "When we reintroduced cancer to these mice over 100 days after the initial tumor inoculation, they still had a strong immunological response that protected them."


(13º§) "We wondered, If this works with leukemias, will it also work with solid tumors?" Majeti said. The team tested the same approach using mouse fibrosarcoma, breast cancer, and bone cancer. "The transformation of cancer cells from solid tumors was not as efficient, but we still observed positive results," Majeti said. With all three cancers, the creation of tumor-derived APCs led to significantly improved survival.


(14º§) Lastly, the researchers returned to the original type of acute leukemia. When the human leukemia cell-derived APCs were exposed to human T cells from the same patient, they observed all the signs that would be expected if the APCs were indeed teaching the T cells how to attack the leukemia.


(15º§) "We showed that reprogrammed tumor cells could lead to a durable and systemic attack on the cancer in mice and a similar response with human patient immune cells," Majeti said. "In the future we might be able to take out tumor cells, transform them into APCs and give them back to patients as a therapeutic cancer vaccine."


(16º§) "Ultimately, we might be able to inject RNA into patients and transform enough cells to activate the immune system against cancer without having to take cells out first," Majeti said. "That's science fiction __ this point, but that's the direction we are interested in going."


(17º§) The work was supported by funding from the Ludwig Foundation for Cancer Research, the Emerson Collective Cancer Research Fund, the New York Stem Cell Foundation, the Stinehart-Reed Foundation, the Leukemia and Lymphoma Society, the J. Benjamin Eckenhoff Fund, the Blavatnik Family Fellowship, the Deutsche Forschungsgemainshaft, the Knut and Alice Wallenberg Foundation, the Stanford Human Biology Research Exploration Program, the National Institutes of Health (grant F31CA196029), the American Society of Hematology, the A.P. Giannini Foundation, and the Stanford Cancer Institute.


(adapted)
med.stanford.edu/news/all-news/2023/03/cancer-hematology.html
PROFESSOR INGLÊS - 1 8
Rewrite the sentence "[...], the researchers programmed mouse leukemia cells so that some of them could be induced to transform themselves into APCs" (10º§) in the passive voice.
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Respostas
201: B
202: C
203: A
204: B
205: A
206: E
207: E
208: C
209: D
210: D
211: A
212: D
213: D
214: C
215: D
216: D
217: B
218: B
219: C
220: D