Questões de Concurso Sobre interpretação de texto | reading comprehension em inglês

Foram encontradas 12.963 questões

Q3655130 Inglês
'First there is trust, then passion, then death': Why the 'Virgin Queen' never married

Neil Armstrong

Elizabeth I, daughter of Henry VIII, is the only English queen never to have married. The iconic Tudor monarch's last visit to Kenilworth 450 years ago may hold some clues to her solo reign − as revealed in a new art installation at the castle, depicting betrayal, beheadings and an elaborate declaration of love.

On a July evening in 1575, 41-year-old Queen Elizabeth I arrived at Kenilworth Castle in Warwickshire, UK, for what would be her longest and last visit. She had given the castle to Robert Dudley in 1563 and granted him the title of Earl of Leicester the following year. Dudley was a great favourite of the Queen and is thought to have been her childhood friend. The precise nature of their close relationship was the subject of much gossip.

Prior to the unmarried Queen's arrival, Dudley had given the magnificent castle a major refurb. New buildings had gone up, a new garden had been created and the estate had been landscaped. And the earl pulled out all the stops to lay on extraordinary entertainment in the form of music, dancing, acrobatics, spectacular fireworks and dramatic interludes performed by costumed actors. On the huge mere surrounding the castle, there was a moving island inhabited by the "Lady of the Lake". There was a 24ft (7.3m) dolphin that concealed musicians, and an 18ft-(5.5m) long swimming mermaid.

No expense was spared. It cost Dudley £1,000 ($1,400) a day − millions in today's money, and the whole extravaganza has been interpreted as an elaborate and expensive courtship display; the 16th-Century ruling class's equivalent of hiring a plane to fly a "Marry Me" banner. "The 1575 festivities were an attempt to woo Elizabeth − marriage is a theme in some of the events," Jeremy Ashbee, head curator of properties at English Heritage, tells the BBC. "Dr Elizabeth Goldring, who has made a detailed study of Lord Leicester, has called it 'his last throw of the dice'."

Dudley's gamble seemed to be going swimmingly, but then everything changed. The highlight of the stay was to have been a masque − or performance − on Wednesday 20 July. It never took place. Was it simply a case of bad weather preventing the event, as the official version had it? Or had the monarch got wind of the subject matter and been angered? The masque featured Diana, goddess of chastity, searching for one of her chaste nymphs, pointedly called Zabetta − a version of the name Elizabeth.

It concluded with a messenger of Juno, goddess of marriage, directly addressing Elizabeth, and imploring her not to follow the path of Diana but to marry instead. Dudley had a certain amount of leeway with the Queen, but this perhaps was going too far. Whatever the reason, the masque never took place, and the revelries were over. The Queen remained in her quarters for a few more days before leaving on 27 July.

Elizabeth I, daughter of Henry VIII, is the only English queen never to have married. She came to power in 1558 at the age of 25, inheriting religious, political and financial problems from her two predecessors, her half-brother, Edward VI (1537-1553), and her half-sister, Mary I (1516-1558).

Advisers and members of Parliament repeatedly urged her to marry to protect England's security. A woman ruling alone? Inconceivable. A queen needed to marry, it was believed, not just to produce a male heir in order to avoid succession disputes but also so that a man could take charge of political and military matters. The entreaties to marry were ceaseless, and numerous matrimonial candidates were suggested or suggested themselves. Elizabeth repeatedly parried, deflected and refused. Why?

It's entirely possible that she simply found the idea of having to obey or defer to a husband − any husband − intolerable. After all, she was very well educated (she learned five languages − French, Italian, Spanish, Latin and Flemish − and had studied history and rhetoric), highly intelligent, proud and fiery. She is said to have declared: "I will have but one mistress here and no master."

Also, Elizabeth knew that a woman could govern perfectly well without a man looking over her shoulder. In the summer of 1544, at Hampton Court, she witnessed the scholarly Katherine Parr, Henry's sixth wife, ruling with full authority while the king was on campaign in France. Katherine was a more than capable regent, and Elizabeth seems to have been profoundly influenced by seeing her stepmother exercising power, and accepting as her due the humble deference of powerful male ministers and courtiers.

Besides, her own immediate family had hardly furnished her with an image of the joys of marriage. Her father had her mother, Anne Boleyn, arrested on trumped-up charges of adultery and conspiracy, and then, shockingly, had her beheaded when Elizabeth was just three years old. Some commentators have suggested that Elizabeth might have been afraid of sex.

In fact, Elizabeth enjoyed the company of handsome men, and could be flirtatious with them. However, she had plenty of reasons to fear pregnancy and childbirth. Childbirth was a very high-risk enterprise in the Tudor era. Jane Seymour, Henry's third wife, died in childbirth, and Katherine Parr died of an illness shortly after giving birth, as had Elizabeth's grandmother, Elizabeth of York.

But there were political reasons, as well as personal, for not marrying. Keeping the country free from the influence of foreign powers may have been a consideration. Also, the prospect of Elizabeth's hand in marriage might have strengthened her negotiating position in her dealings with France, Spain and other nations. Meanwhile, if she'd married an English nobleman (and Dudley might have been a possibility had not his wife, Amy Robsart, died in somewhat suspicious circumstances in 1560), she would have automatically put another English nobleman's nose out-of-joint.

So she kept everyone waiting and wondering. She seems to have had an instinctive grasp of what we now call PR, and liked to present herself as wholly devoted to her realm. From early in her reign she cultivated the image of the Virgin Queen. In 1559 she declared, in response to MPs asking her to marry, that eventually "a marble stone shall declare that a queen, having reigned such a time, lived and died a virgin".

Had the real Elizabeth allowed Dudley to think he might be in with a chance? And what did the Kenilworth visit mean for their relationship? "I don't believe that he felt humiliated by her rejection of his proposal," says Ashbee. "He was happy for an official account of the festivities to be published soon afterwards, and in his will, he stipulated that the castle was to be left exactly as it had been. I rather get the feeling that he saw 1575 as his 'finest hour'. He certainly didn't retire quietly into private life after 1575."

Elizabeth was furious with Dudley for a while when he married Lettice Knollys in 1578 − but she forgave him. When he died, in 1588, she locked herself in her room for so long that her chief adviser ordered that the doors be forced open. And when Elizabeth died in 1603, a note Dudley had sent her shortly before his death was found in a casket she kept by the side of her bed. She had written on it "his last letter".


https://www.bbc.com/culture/article/20250714-why-the-virgin-queen-nev er-married (adapted)

Professor Ana wants her students to produce texts based on everyday situations, connecting them to the historical narrative about Elizabeth I. She plans activities where students write diary entries, letters, or news reports, imagining themselves in Tudor England or comparing past and present relationship customs. Her objective is to promote meaningful writing through relevant communicative contexts.
Analyze the statements about contextualized text production:
(__)Contextualized writing activities motivate students by connecting historical content to contemporary experiences and interests.
(__)Text production should focus primarily on grammatical accuracy, with content relevance being a secondary consideration.
(__)Creative writing based on historical texts develops both linguistic competence and cultural understanding simultaneously.
(__)Everyday situations provide authentic contexts for language use, making writing more meaningful and engaging for students.

Correct sequence of TRUE (T) or FALSE (F):
Alternativas
Q3655129 Inglês
'First there is trust, then passion, then death': Why the 'Virgin Queen' never married

Neil Armstrong

Elizabeth I, daughter of Henry VIII, is the only English queen never to have married. The iconic Tudor monarch's last visit to Kenilworth 450 years ago may hold some clues to her solo reign − as revealed in a new art installation at the castle, depicting betrayal, beheadings and an elaborate declaration of love.

On a July evening in 1575, 41-year-old Queen Elizabeth I arrived at Kenilworth Castle in Warwickshire, UK, for what would be her longest and last visit. She had given the castle to Robert Dudley in 1563 and granted him the title of Earl of Leicester the following year. Dudley was a great favourite of the Queen and is thought to have been her childhood friend. The precise nature of their close relationship was the subject of much gossip.

Prior to the unmarried Queen's arrival, Dudley had given the magnificent castle a major refurb. New buildings had gone up, a new garden had been created and the estate had been landscaped. And the earl pulled out all the stops to lay on extraordinary entertainment in the form of music, dancing, acrobatics, spectacular fireworks and dramatic interludes performed by costumed actors. On the huge mere surrounding the castle, there was a moving island inhabited by the "Lady of the Lake". There was a 24ft (7.3m) dolphin that concealed musicians, and an 18ft-(5.5m) long swimming mermaid.

No expense was spared. It cost Dudley £1,000 ($1,400) a day − millions in today's money, and the whole extravaganza has been interpreted as an elaborate and expensive courtship display; the 16th-Century ruling class's equivalent of hiring a plane to fly a "Marry Me" banner. "The 1575 festivities were an attempt to woo Elizabeth − marriage is a theme in some of the events," Jeremy Ashbee, head curator of properties at English Heritage, tells the BBC. "Dr Elizabeth Goldring, who has made a detailed study of Lord Leicester, has called it 'his last throw of the dice'."

Dudley's gamble seemed to be going swimmingly, but then everything changed. The highlight of the stay was to have been a masque − or performance − on Wednesday 20 July. It never took place. Was it simply a case of bad weather preventing the event, as the official version had it? Or had the monarch got wind of the subject matter and been angered? The masque featured Diana, goddess of chastity, searching for one of her chaste nymphs, pointedly called Zabetta − a version of the name Elizabeth.

It concluded with a messenger of Juno, goddess of marriage, directly addressing Elizabeth, and imploring her not to follow the path of Diana but to marry instead. Dudley had a certain amount of leeway with the Queen, but this perhaps was going too far. Whatever the reason, the masque never took place, and the revelries were over. The Queen remained in her quarters for a few more days before leaving on 27 July.

Elizabeth I, daughter of Henry VIII, is the only English queen never to have married. She came to power in 1558 at the age of 25, inheriting religious, political and financial problems from her two predecessors, her half-brother, Edward VI (1537-1553), and her half-sister, Mary I (1516-1558).

Advisers and members of Parliament repeatedly urged her to marry to protect England's security. A woman ruling alone? Inconceivable. A queen needed to marry, it was believed, not just to produce a male heir in order to avoid succession disputes but also so that a man could take charge of political and military matters. The entreaties to marry were ceaseless, and numerous matrimonial candidates were suggested or suggested themselves. Elizabeth repeatedly parried, deflected and refused. Why?

It's entirely possible that she simply found the idea of having to obey or defer to a husband − any husband − intolerable. After all, she was very well educated (she learned five languages − French, Italian, Spanish, Latin and Flemish − and had studied history and rhetoric), highly intelligent, proud and fiery. She is said to have declared: "I will have but one mistress here and no master."

Also, Elizabeth knew that a woman could govern perfectly well without a man looking over her shoulder. In the summer of 1544, at Hampton Court, she witnessed the scholarly Katherine Parr, Henry's sixth wife, ruling with full authority while the king was on campaign in France. Katherine was a more than capable regent, and Elizabeth seems to have been profoundly influenced by seeing her stepmother exercising power, and accepting as her due the humble deference of powerful male ministers and courtiers.

Besides, her own immediate family had hardly furnished her with an image of the joys of marriage. Her father had her mother, Anne Boleyn, arrested on trumped-up charges of adultery and conspiracy, and then, shockingly, had her beheaded when Elizabeth was just three years old. Some commentators have suggested that Elizabeth might have been afraid of sex.

In fact, Elizabeth enjoyed the company of handsome men, and could be flirtatious with them. However, she had plenty of reasons to fear pregnancy and childbirth. Childbirth was a very high-risk enterprise in the Tudor era. Jane Seymour, Henry's third wife, died in childbirth, and Katherine Parr died of an illness shortly after giving birth, as had Elizabeth's grandmother, Elizabeth of York.

But there were political reasons, as well as personal, for not marrying. Keeping the country free from the influence of foreign powers may have been a consideration. Also, the prospect of Elizabeth's hand in marriage might have strengthened her negotiating position in her dealings with France, Spain and other nations. Meanwhile, if she'd married an English nobleman (and Dudley might have been a possibility had not his wife, Amy Robsart, died in somewhat suspicious circumstances in 1560), she would have automatically put another English nobleman's nose out-of-joint.

So she kept everyone waiting and wondering. She seems to have had an instinctive grasp of what we now call PR, and liked to present herself as wholly devoted to her realm. From early in her reign she cultivated the image of the Virgin Queen. In 1559 she declared, in response to MPs asking her to marry, that eventually "a marble stone shall declare that a queen, having reigned such a time, lived and died a virgin".

Had the real Elizabeth allowed Dudley to think he might be in with a chance? And what did the Kenilworth visit mean for their relationship? "I don't believe that he felt humiliated by her rejection of his proposal," says Ashbee. "He was happy for an official account of the festivities to be published soon afterwards, and in his will, he stipulated that the castle was to be left exactly as it had been. I rather get the feeling that he saw 1575 as his 'finest hour'. He certainly didn't retire quietly into private life after 1575."

Elizabeth was furious with Dudley for a while when he married Lettice Knollys in 1578 − but she forgave him. When he died, in 1588, she locked herself in her room for so long that her chief adviser ordered that the doors be forced open. And when Elizabeth died in 1603, a note Dudley had sent her shortly before his death was found in a casket she kept by the side of her bed. She had written on it "his last letter".


https://www.bbc.com/culture/article/20250714-why-the-virgin-queen-nev er-married (adapted)

Read the excerpt below:
Professor Roberto is discussing the cultural aspects presented in the Elizabeth I text with his students. He emphasizes how understanding Tudor society, marriage customs, and political arrangements helps students develop intercultural competence. The teacher wants to explore how historical contexts influence language use and meaning construction in different cultural settings. The study of foreign language through cultural texts like the Elizabeth I story promotes _______ by exposing students to different historical periods, social values, and communication patterns.
Fill in the blank above and select the correct alternative.
Alternativas
Q3655128 Inglês
'First there is trust, then passion, then death': Why the 'Virgin Queen' never married

Neil Armstrong

Elizabeth I, daughter of Henry VIII, is the only English queen never to have married. The iconic Tudor monarch's last visit to Kenilworth 450 years ago may hold some clues to her solo reign − as revealed in a new art installation at the castle, depicting betrayal, beheadings and an elaborate declaration of love.

On a July evening in 1575, 41-year-old Queen Elizabeth I arrived at Kenilworth Castle in Warwickshire, UK, for what would be her longest and last visit. She had given the castle to Robert Dudley in 1563 and granted him the title of Earl of Leicester the following year. Dudley was a great favourite of the Queen and is thought to have been her childhood friend. The precise nature of their close relationship was the subject of much gossip.

Prior to the unmarried Queen's arrival, Dudley had given the magnificent castle a major refurb. New buildings had gone up, a new garden had been created and the estate had been landscaped. And the earl pulled out all the stops to lay on extraordinary entertainment in the form of music, dancing, acrobatics, spectacular fireworks and dramatic interludes performed by costumed actors. On the huge mere surrounding the castle, there was a moving island inhabited by the "Lady of the Lake". There was a 24ft (7.3m) dolphin that concealed musicians, and an 18ft-(5.5m) long swimming mermaid.

No expense was spared. It cost Dudley £1,000 ($1,400) a day − millions in today's money, and the whole extravaganza has been interpreted as an elaborate and expensive courtship display; the 16th-Century ruling class's equivalent of hiring a plane to fly a "Marry Me" banner. "The 1575 festivities were an attempt to woo Elizabeth − marriage is a theme in some of the events," Jeremy Ashbee, head curator of properties at English Heritage, tells the BBC. "Dr Elizabeth Goldring, who has made a detailed study of Lord Leicester, has called it 'his last throw of the dice'."

Dudley's gamble seemed to be going swimmingly, but then everything changed. The highlight of the stay was to have been a masque − or performance − on Wednesday 20 July. It never took place. Was it simply a case of bad weather preventing the event, as the official version had it? Or had the monarch got wind of the subject matter and been angered? The masque featured Diana, goddess of chastity, searching for one of her chaste nymphs, pointedly called Zabetta − a version of the name Elizabeth.

It concluded with a messenger of Juno, goddess of marriage, directly addressing Elizabeth, and imploring her not to follow the path of Diana but to marry instead. Dudley had a certain amount of leeway with the Queen, but this perhaps was going too far. Whatever the reason, the masque never took place, and the revelries were over. The Queen remained in her quarters for a few more days before leaving on 27 July.

Elizabeth I, daughter of Henry VIII, is the only English queen never to have married. She came to power in 1558 at the age of 25, inheriting religious, political and financial problems from her two predecessors, her half-brother, Edward VI (1537-1553), and her half-sister, Mary I (1516-1558).

Advisers and members of Parliament repeatedly urged her to marry to protect England's security. A woman ruling alone? Inconceivable. A queen needed to marry, it was believed, not just to produce a male heir in order to avoid succession disputes but also so that a man could take charge of political and military matters. The entreaties to marry were ceaseless, and numerous matrimonial candidates were suggested or suggested themselves. Elizabeth repeatedly parried, deflected and refused. Why?

It's entirely possible that she simply found the idea of having to obey or defer to a husband − any husband − intolerable. After all, she was very well educated (she learned five languages − French, Italian, Spanish, Latin and Flemish − and had studied history and rhetoric), highly intelligent, proud and fiery. She is said to have declared: "I will have but one mistress here and no master."

Also, Elizabeth knew that a woman could govern perfectly well without a man looking over her shoulder. In the summer of 1544, at Hampton Court, she witnessed the scholarly Katherine Parr, Henry's sixth wife, ruling with full authority while the king was on campaign in France. Katherine was a more than capable regent, and Elizabeth seems to have been profoundly influenced by seeing her stepmother exercising power, and accepting as her due the humble deference of powerful male ministers and courtiers.

Besides, her own immediate family had hardly furnished her with an image of the joys of marriage. Her father had her mother, Anne Boleyn, arrested on trumped-up charges of adultery and conspiracy, and then, shockingly, had her beheaded when Elizabeth was just three years old. Some commentators have suggested that Elizabeth might have been afraid of sex.

In fact, Elizabeth enjoyed the company of handsome men, and could be flirtatious with them. However, she had plenty of reasons to fear pregnancy and childbirth. Childbirth was a very high-risk enterprise in the Tudor era. Jane Seymour, Henry's third wife, died in childbirth, and Katherine Parr died of an illness shortly after giving birth, as had Elizabeth's grandmother, Elizabeth of York.

But there were political reasons, as well as personal, for not marrying. Keeping the country free from the influence of foreign powers may have been a consideration. Also, the prospect of Elizabeth's hand in marriage might have strengthened her negotiating position in her dealings with France, Spain and other nations. Meanwhile, if she'd married an English nobleman (and Dudley might have been a possibility had not his wife, Amy Robsart, died in somewhat suspicious circumstances in 1560), she would have automatically put another English nobleman's nose out-of-joint.

So she kept everyone waiting and wondering. She seems to have had an instinctive grasp of what we now call PR, and liked to present herself as wholly devoted to her realm. From early in her reign she cultivated the image of the Virgin Queen. In 1559 she declared, in response to MPs asking her to marry, that eventually "a marble stone shall declare that a queen, having reigned such a time, lived and died a virgin".

Had the real Elizabeth allowed Dudley to think he might be in with a chance? And what did the Kenilworth visit mean for their relationship? "I don't believe that he felt humiliated by her rejection of his proposal," says Ashbee. "He was happy for an official account of the festivities to be published soon afterwards, and in his will, he stipulated that the castle was to be left exactly as it had been. I rather get the feeling that he saw 1575 as his 'finest hour'. He certainly didn't retire quietly into private life after 1575."

Elizabeth was furious with Dudley for a while when he married Lettice Knollys in 1578 − but she forgave him. When he died, in 1588, she locked herself in her room for so long that her chief adviser ordered that the doors be forced open. And when Elizabeth died in 1603, a note Dudley had sent her shortly before his death was found in a casket she kept by the side of her bed. She had written on it "his last letter".


https://www.bbc.com/culture/article/20250714-why-the-virgin-queen-nev er-married (adapted)

Professor Carlos is preparing a lesson plan based on the Elizabeth I text for his high school students. He needs to establish clear learning objectives that integrate reading comprehension, vocabulary development, and cultural understanding. His goal is to create a coherent didactic sequence that aligns with Base Nacional Comum Curricular (BNCC) competencies for foreign language teaching. Regarding this topic, select the INCORRECT alternative.
Alternativas
Q3655126 Inglês
'First there is trust, then passion, then death': Why the 'Virgin Queen' never married

Neil Armstrong

Elizabeth I, daughter of Henry VIII, is the only English queen never to have married. The iconic Tudor monarch's last visit to Kenilworth 450 years ago may hold some clues to her solo reign − as revealed in a new art installation at the castle, depicting betrayal, beheadings and an elaborate declaration of love.

On a July evening in 1575, 41-year-old Queen Elizabeth I arrived at Kenilworth Castle in Warwickshire, UK, for what would be her longest and last visit. She had given the castle to Robert Dudley in 1563 and granted him the title of Earl of Leicester the following year. Dudley was a great favourite of the Queen and is thought to have been her childhood friend. The precise nature of their close relationship was the subject of much gossip.

Prior to the unmarried Queen's arrival, Dudley had given the magnificent castle a major refurb. New buildings had gone up, a new garden had been created and the estate had been landscaped. And the earl pulled out all the stops to lay on extraordinary entertainment in the form of music, dancing, acrobatics, spectacular fireworks and dramatic interludes performed by costumed actors. On the huge mere surrounding the castle, there was a moving island inhabited by the "Lady of the Lake". There was a 24ft (7.3m) dolphin that concealed musicians, and an 18ft-(5.5m) long swimming mermaid.

No expense was spared. It cost Dudley £1,000 ($1,400) a day − millions in today's money, and the whole extravaganza has been interpreted as an elaborate and expensive courtship display; the 16th-Century ruling class's equivalent of hiring a plane to fly a "Marry Me" banner. "The 1575 festivities were an attempt to woo Elizabeth − marriage is a theme in some of the events," Jeremy Ashbee, head curator of properties at English Heritage, tells the BBC. "Dr Elizabeth Goldring, who has made a detailed study of Lord Leicester, has called it 'his last throw of the dice'."

Dudley's gamble seemed to be going swimmingly, but then everything changed. The highlight of the stay was to have been a masque − or performance − on Wednesday 20 July. It never took place. Was it simply a case of bad weather preventing the event, as the official version had it? Or had the monarch got wind of the subject matter and been angered? The masque featured Diana, goddess of chastity, searching for one of her chaste nymphs, pointedly called Zabetta − a version of the name Elizabeth.

It concluded with a messenger of Juno, goddess of marriage, directly addressing Elizabeth, and imploring her not to follow the path of Diana but to marry instead. Dudley had a certain amount of leeway with the Queen, but this perhaps was going too far. Whatever the reason, the masque never took place, and the revelries were over. The Queen remained in her quarters for a few more days before leaving on 27 July.

Elizabeth I, daughter of Henry VIII, is the only English queen never to have married. She came to power in 1558 at the age of 25, inheriting religious, political and financial problems from her two predecessors, her half-brother, Edward VI (1537-1553), and her half-sister, Mary I (1516-1558).

Advisers and members of Parliament repeatedly urged her to marry to protect England's security. A woman ruling alone? Inconceivable. A queen needed to marry, it was believed, not just to produce a male heir in order to avoid succession disputes but also so that a man could take charge of political and military matters. The entreaties to marry were ceaseless, and numerous matrimonial candidates were suggested or suggested themselves. Elizabeth repeatedly parried, deflected and refused. Why?

It's entirely possible that she simply found the idea of having to obey or defer to a husband − any husband − intolerable. After all, she was very well educated (she learned five languages − French, Italian, Spanish, Latin and Flemish − and had studied history and rhetoric), highly intelligent, proud and fiery. She is said to have declared: "I will have but one mistress here and no master."

Also, Elizabeth knew that a woman could govern perfectly well without a man looking over her shoulder. In the summer of 1544, at Hampton Court, she witnessed the scholarly Katherine Parr, Henry's sixth wife, ruling with full authority while the king was on campaign in France. Katherine was a more than capable regent, and Elizabeth seems to have been profoundly influenced by seeing her stepmother exercising power, and accepting as her due the humble deference of powerful male ministers and courtiers.

Besides, her own immediate family had hardly furnished her with an image of the joys of marriage. Her father had her mother, Anne Boleyn, arrested on trumped-up charges of adultery and conspiracy, and then, shockingly, had her beheaded when Elizabeth was just three years old. Some commentators have suggested that Elizabeth might have been afraid of sex.

In fact, Elizabeth enjoyed the company of handsome men, and could be flirtatious with them. However, she had plenty of reasons to fear pregnancy and childbirth. Childbirth was a very high-risk enterprise in the Tudor era. Jane Seymour, Henry's third wife, died in childbirth, and Katherine Parr died of an illness shortly after giving birth, as had Elizabeth's grandmother, Elizabeth of York.

But there were political reasons, as well as personal, for not marrying. Keeping the country free from the influence of foreign powers may have been a consideration. Also, the prospect of Elizabeth's hand in marriage might have strengthened her negotiating position in her dealings with France, Spain and other nations. Meanwhile, if she'd married an English nobleman (and Dudley might have been a possibility had not his wife, Amy Robsart, died in somewhat suspicious circumstances in 1560), she would have automatically put another English nobleman's nose out-of-joint.

So she kept everyone waiting and wondering. She seems to have had an instinctive grasp of what we now call PR, and liked to present herself as wholly devoted to her realm. From early in her reign she cultivated the image of the Virgin Queen. In 1559 she declared, in response to MPs asking her to marry, that eventually "a marble stone shall declare that a queen, having reigned such a time, lived and died a virgin".

Had the real Elizabeth allowed Dudley to think he might be in with a chance? And what did the Kenilworth visit mean for their relationship? "I don't believe that he felt humiliated by her rejection of his proposal," says Ashbee. "He was happy for an official account of the festivities to be published soon afterwards, and in his will, he stipulated that the castle was to be left exactly as it had been. I rather get the feeling that he saw 1575 as his 'finest hour'. He certainly didn't retire quietly into private life after 1575."

Elizabeth was furious with Dudley for a while when he married Lettice Knollys in 1578 − but she forgave him. When he died, in 1588, she locked herself in her room for so long that her chief adviser ordered that the doors be forced open. And when Elizabeth died in 1603, a note Dudley had sent her shortly before his death was found in a casket she kept by the side of her bed. She had written on it "his last letter".


https://www.bbc.com/culture/article/20250714-why-the-virgin-queen-nev er-married (adapted)

Consider the following statements about reading methods applied to the Elizabeth I text:
I. Skimming techniques help students identify the main ideas about the Queen's relationship with Robert Dudley.
II. Scanning allows students to locate specific information such as dates, places, and historical facts mentioned in the text.
III. Pre-reading activities should activate students' background knowledge about Tudor England and royal marriage customs.
IV. Reading comprehension depends solely on vocabulary knowledge, making cultural context irrelevant for understanding.

Which statements are correct?
Alternativas
Q3655125 Inglês
'First there is trust, then passion, then death': Why the 'Virgin Queen' never married

Neil Armstrong

Elizabeth I, daughter of Henry VIII, is the only English queen never to have married. The iconic Tudor monarch's last visit to Kenilworth 450 years ago may hold some clues to her solo reign − as revealed in a new art installation at the castle, depicting betrayal, beheadings and an elaborate declaration of love.

On a July evening in 1575, 41-year-old Queen Elizabeth I arrived at Kenilworth Castle in Warwickshire, UK, for what would be her longest and last visit. She had given the castle to Robert Dudley in 1563 and granted him the title of Earl of Leicester the following year. Dudley was a great favourite of the Queen and is thought to have been her childhood friend. The precise nature of their close relationship was the subject of much gossip.

Prior to the unmarried Queen's arrival, Dudley had given the magnificent castle a major refurb. New buildings had gone up, a new garden had been created and the estate had been landscaped. And the earl pulled out all the stops to lay on extraordinary entertainment in the form of music, dancing, acrobatics, spectacular fireworks and dramatic interludes performed by costumed actors. On the huge mere surrounding the castle, there was a moving island inhabited by the "Lady of the Lake". There was a 24ft (7.3m) dolphin that concealed musicians, and an 18ft-(5.5m) long swimming mermaid.

No expense was spared. It cost Dudley £1,000 ($1,400) a day − millions in today's money, and the whole extravaganza has been interpreted as an elaborate and expensive courtship display; the 16th-Century ruling class's equivalent of hiring a plane to fly a "Marry Me" banner. "The 1575 festivities were an attempt to woo Elizabeth − marriage is a theme in some of the events," Jeremy Ashbee, head curator of properties at English Heritage, tells the BBC. "Dr Elizabeth Goldring, who has made a detailed study of Lord Leicester, has called it 'his last throw of the dice'."

Dudley's gamble seemed to be going swimmingly, but then everything changed. The highlight of the stay was to have been a masque − or performance − on Wednesday 20 July. It never took place. Was it simply a case of bad weather preventing the event, as the official version had it? Or had the monarch got wind of the subject matter and been angered? The masque featured Diana, goddess of chastity, searching for one of her chaste nymphs, pointedly called Zabetta − a version of the name Elizabeth.

It concluded with a messenger of Juno, goddess of marriage, directly addressing Elizabeth, and imploring her not to follow the path of Diana but to marry instead. Dudley had a certain amount of leeway with the Queen, but this perhaps was going too far. Whatever the reason, the masque never took place, and the revelries were over. The Queen remained in her quarters for a few more days before leaving on 27 July.

Elizabeth I, daughter of Henry VIII, is the only English queen never to have married. She came to power in 1558 at the age of 25, inheriting religious, political and financial problems from her two predecessors, her half-brother, Edward VI (1537-1553), and her half-sister, Mary I (1516-1558).

Advisers and members of Parliament repeatedly urged her to marry to protect England's security. A woman ruling alone? Inconceivable. A queen needed to marry, it was believed, not just to produce a male heir in order to avoid succession disputes but also so that a man could take charge of political and military matters. The entreaties to marry were ceaseless, and numerous matrimonial candidates were suggested or suggested themselves. Elizabeth repeatedly parried, deflected and refused. Why?

It's entirely possible that she simply found the idea of having to obey or defer to a husband − any husband − intolerable. After all, she was very well educated (she learned five languages − French, Italian, Spanish, Latin and Flemish − and had studied history and rhetoric), highly intelligent, proud and fiery. She is said to have declared: "I will have but one mistress here and no master."

Also, Elizabeth knew that a woman could govern perfectly well without a man looking over her shoulder. In the summer of 1544, at Hampton Court, she witnessed the scholarly Katherine Parr, Henry's sixth wife, ruling with full authority while the king was on campaign in France. Katherine was a more than capable regent, and Elizabeth seems to have been profoundly influenced by seeing her stepmother exercising power, and accepting as her due the humble deference of powerful male ministers and courtiers.

Besides, her own immediate family had hardly furnished her with an image of the joys of marriage. Her father had her mother, Anne Boleyn, arrested on trumped-up charges of adultery and conspiracy, and then, shockingly, had her beheaded when Elizabeth was just three years old. Some commentators have suggested that Elizabeth might have been afraid of sex.

In fact, Elizabeth enjoyed the company of handsome men, and could be flirtatious with them. However, she had plenty of reasons to fear pregnancy and childbirth. Childbirth was a very high-risk enterprise in the Tudor era. Jane Seymour, Henry's third wife, died in childbirth, and Katherine Parr died of an illness shortly after giving birth, as had Elizabeth's grandmother, Elizabeth of York.

But there were political reasons, as well as personal, for not marrying. Keeping the country free from the influence of foreign powers may have been a consideration. Also, the prospect of Elizabeth's hand in marriage might have strengthened her negotiating position in her dealings with France, Spain and other nations. Meanwhile, if she'd married an English nobleman (and Dudley might have been a possibility had not his wife, Amy Robsart, died in somewhat suspicious circumstances in 1560), she would have automatically put another English nobleman's nose out-of-joint.

So she kept everyone waiting and wondering. She seems to have had an instinctive grasp of what we now call PR, and liked to present herself as wholly devoted to her realm. From early in her reign she cultivated the image of the Virgin Queen. In 1559 she declared, in response to MPs asking her to marry, that eventually "a marble stone shall declare that a queen, having reigned such a time, lived and died a virgin".

Had the real Elizabeth allowed Dudley to think he might be in with a chance? And what did the Kenilworth visit mean for their relationship? "I don't believe that he felt humiliated by her rejection of his proposal," says Ashbee. "He was happy for an official account of the festivities to be published soon afterwards, and in his will, he stipulated that the castle was to be left exactly as it had been. I rather get the feeling that he saw 1575 as his 'finest hour'. He certainly didn't retire quietly into private life after 1575."

Elizabeth was furious with Dudley for a while when he married Lettice Knollys in 1578 − but she forgave him. When he died, in 1588, she locked herself in her room for so long that her chief adviser ordered that the doors be forced open. And when Elizabeth died in 1603, a note Dudley had sent her shortly before his death was found in a casket she kept by the side of her bed. She had written on it "his last letter".


https://www.bbc.com/culture/article/20250714-why-the-virgin-queen-nev er-married (adapted)

Teacher Sandra wants to develop integrated language skills using the Elizabeth I text. She plans activities that combine reading comprehension with speaking practice, listening exercises with writing tasks. Her objective is to create meaningful connections between the four language skills while exploring the historical content about the Virgin Queen.
Analyze the statements about integrated language skills and indicate the correct sequence of TRUE (T) or FALSE (F):
(__)Integrated skills activities promote more authentic language use, reflecting real-world communication situations.
(__)Speaking activities should be isolated from reading tasks to avoid confusion in language processing.
(__)Listening skills can be developed through audio materials about Elizabethan England, connecting to the written text.
(__)Writing tasks based on the text should focus exclusively on grammar exercises, separating content from form.

The CORRECT sequence is:
Alternativas
Q3653788 Inglês
For beginners, the use of TPR (Total Physical Response) is effective because it:
Alternativas
Q3653776 Inglês
What is the ideal balance between TTT and STT in the classroom?
Alternativas
Q3652508 Inglês
In the sentence “After three drafts and several peer reviews, the remaining errors were negligible for publication”, infer the meaning of the word “negligible” from context:
Alternativas
Q3652507 Inglês
Consider the paragraph “The school extended library hours during exams. However, usage decreased in the first week. Therefore, the staff planned workshops on research skills.” Identify how the marker “However” guides the relation between the first two sentences:
Alternativas
Q3652506 Inglês
Observe the notice “Wash hands before entering the lab. Wear goggles at all times. Report spills to the teacher immediately.” Identify the genre and communicative intention represented by the excerpt:
Alternativas
Q3652505 Inglês
Read the two sentences “Ms Lee met the parents, and they asked about the new schedule. This helped the team plan the workshops.” Identify the referent of the deictic “This” in the second sentence:
Alternativas
Q3650844 Inglês
The act of reading is not a passive activity of decoding words, but rather an interactive process that requires interpretation, contextualization, and critical reflection. In academic environments, the relationship between reading and text production becomes central, since one influences and enriches the other. Based on this perspective, which of the following statements represents this relationship?
Alternativas
Q3650840 Inglês
In the teaching of English as a foreign language, the development of reading skills goes beyond the recognition of vocabulary and grammatical structures. It involves strategies that promote comprehension, inference, and critical analysis of texts. Considering contemporary approaches to English teaching, which of the following alternatives reflects the role of reading in language learning?
Alternativas
Q3650837 Inglês
During a training session on text genres, teachers were asked to point out an example that clearly represents a written academic text genre commonly used in education. Which option is correct?
Alternativas
Q3650832 Inglês
O texto seguinte servirá de base para responder à questão.

Big Data Begins to Crack the Case of Endometriosis

Records from millions of patients at University of California health centers found correlations between endometriosis, one of the most common diseases in women, and a bounty of other diseases.

By Levi Gadye

Scientists at UC San Francisco have found that endometriosis — a painful chronic disease that often goes undiagnosed yet is estimated to affect as many as 200 million women worldwide — frequently occurs alongside conditions like cancer, Crohn's disease, and migraine.

The research could improve diagnosis and, ultimately, treatments for endometriosis, preventing women from having to go on long diagnostic journeys in which they are told that nothing is wrong with them.

The study, which appeared in Cell Reports Medicine on July 31, used computational methods developed at UCSF to analyze anonymized patient records collected at the University of California's six health centers.

"We now have both the tools and the data to make a difference for the huge population that suffers from endometriosis," said Marina Sirota, PhD, the interim director of the UCSF Bakar Computational Health Sciences Institute (BCHSI), professor of pediatrics, and senior author of the paper. "We hope this can spur a sea change in how we approach this disorder."

"The impact on patients' lives is huge"

Endometriosis, often called 'endo,' occurs when the endometrium, the blood-rich tissue that grows in the uterus before being expelled each month during menstruation, spreads to other nearby organs. It causes chronic pain and infertility. It is estimated that nearly 10% of women worldwide suffer from it.

"Endo is extremely debilitating," said Linda Giudice, MD, PhD, MSc, a physician-scientist in the Department of Obstetrics, Gynecology and Reproductive Sciences at UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal relationships to being able to hold a job, have a family, and maintain psychological wellbeing."

The gold standard to diagnose endometriosis is surgery to find endometrial tissue outside of the uterus, and it is mainly treated with hormones to suppress the menstrual cycle, or surgery to remove the excess tissue.

But not everyone responds to hormonal therapy, which can have debilitating side effects. Even after surgery, the condition can flare up. Removal of the uterus is a last-ditch measure that is usually reserved for older women; but some women continue to experience pain even after a hysterectomy.

Giudice partnered with Sirota to leverage the UC health system's anonymized patient data against endo, which can vary dramatically across patients. Both Giudice and Sirota are principal investigators at the UCSF-Stanford Endometriosis Center for Discovery, Innovation, Training and Community Engagement (ENACT).

"This data is messy; it was not collected for research purposes but for the real, human purpose of helping women who need care," Sirota said. "We had the rare chance to rigorously assess how endometriosis presents across UCSF's patient population and then ask whether these observations held true with patients seen at the other UC health centers."

Data connects the dots for understanding endometriosis

Using algorithms developed for the task, Umair Khan, a bioinformatics graduate student in Sirota's lab and first author of the paper, hunted for connections linking endometriosis with the rest of each patient's health history.

He compared endo patients with patients who did not have it, and categorized the patients with endo into groups based on shared health histories. He mapped his findings from the UCSF data against the rest of the UC's health data to see if they held up across California.

"We found over 600 correlations between endometriosis and other conditions," Khan said. "These ranged from what we already knew or suspected, like infertility, autoimmune disease, and acid-reflux, to the unexpected, like certain cancers, asthma, and eye-related diseases."

Some patients had migraines, bolstering previous studies suggesting that migraine drugs might help treat endometriosis.

"In the past, studies like this would have been nearly impossible," said Tomiko Oskotsky, MD, an investigator at ENACT, associate professor in UCSF BCHSI, and co-author of the paper. "It was only 12 years ago that de-identified electronic health records became available at this scale."

The study supports the growing understanding of endometriosis as a "multi-system" disorder — a disease arising from dysfunction throughout the body.

"This is the kind of data we need to move the needle, which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually, we hope, tailored treatment for the millions of women who suffer from endometriosis."


https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case -endometriosis
Considering the final section of the text, where Giudice states "We're finally getting closer to faster diagnosis and, eventually, tailored treatment for the millions of women who suffer from endometriosis", what does this conclusion primarily contribute to the text's coherence?
Alternativas
Q3650829 Inglês
O texto seguinte servirá de base para responder à questão.

Big Data Begins to Crack the Case of Endometriosis

Records from millions of patients at University of California health centers found correlations between endometriosis, one of the most common diseases in women, and a bounty of other diseases.

By Levi Gadye

Scientists at UC San Francisco have found that endometriosis — a painful chronic disease that often goes undiagnosed yet is estimated to affect as many as 200 million women worldwide — frequently occurs alongside conditions like cancer, Crohn's disease, and migraine.

The research could improve diagnosis and, ultimately, treatments for endometriosis, preventing women from having to go on long diagnostic journeys in which they are told that nothing is wrong with them.

The study, which appeared in Cell Reports Medicine on July 31, used computational methods developed at UCSF to analyze anonymized patient records collected at the University of California's six health centers.

"We now have both the tools and the data to make a difference for the huge population that suffers from endometriosis," said Marina Sirota, PhD, the interim director of the UCSF Bakar Computational Health Sciences Institute (BCHSI), professor of pediatrics, and senior author of the paper. "We hope this can spur a sea change in how we approach this disorder."

"The impact on patients' lives is huge"

Endometriosis, often called 'endo,' occurs when the endometrium, the blood-rich tissue that grows in the uterus before being expelled each month during menstruation, spreads to other nearby organs. It causes chronic pain and infertility. It is estimated that nearly 10% of women worldwide suffer from it.

"Endo is extremely debilitating," said Linda Giudice, MD, PhD, MSc, a physician-scientist in the Department of Obstetrics, Gynecology and Reproductive Sciences at UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal relationships to being able to hold a job, have a family, and maintain psychological wellbeing."

The gold standard to diagnose endometriosis is surgery to find endometrial tissue outside of the uterus, and it is mainly treated with hormones to suppress the menstrual cycle, or surgery to remove the excess tissue.

But not everyone responds to hormonal therapy, which can have debilitating side effects. Even after surgery, the condition can flare up. Removal of the uterus is a last-ditch measure that is usually reserved for older women; but some women continue to experience pain even after a hysterectomy.

Giudice partnered with Sirota to leverage the UC health system's anonymized patient data against endo, which can vary dramatically across patients. Both Giudice and Sirota are principal investigators at the UCSF-Stanford Endometriosis Center for Discovery, Innovation, Training and Community Engagement (ENACT).

"This data is messy; it was not collected for research purposes but for the real, human purpose of helping women who need care," Sirota said. "We had the rare chance to rigorously assess how endometriosis presents across UCSF's patient population and then ask whether these observations held true with patients seen at the other UC health centers."

Data connects the dots for understanding endometriosis

Using algorithms developed for the task, Umair Khan, a bioinformatics graduate student in Sirota's lab and first author of the paper, hunted for connections linking endometriosis with the rest of each patient's health history.

He compared endo patients with patients who did not have it, and categorized the patients with endo into groups based on shared health histories. He mapped his findings from the UCSF data against the rest of the UC's health data to see if they held up across California.

"We found over 600 correlations between endometriosis and other conditions," Khan said. "These ranged from what we already knew or suspected, like infertility, autoimmune disease, and acid-reflux, to the unexpected, like certain cancers, asthma, and eye-related diseases."

Some patients had migraines, bolstering previous studies suggesting that migraine drugs might help treat endometriosis.

"In the past, studies like this would have been nearly impossible," said Tomiko Oskotsky, MD, an investigator at ENACT, associate professor in UCSF BCHSI, and co-author of the paper. "It was only 12 years ago that de-identified electronic health records became available at this scale."

The study supports the growing understanding of endometriosis as a "multi-system" disorder — a disease arising from dysfunction throughout the body.

"This is the kind of data we need to move the needle, which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually, we hope, tailored treatment for the millions of women who suffer from endometriosis."


https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case -endometriosis
In the passage "The research could improve diagnosis and, ultimately, treatments for endometriosis, preventing women from having to go on long diagnostic journeys in which they are told that nothing is wrong with them", what is the main purpose of this sentence within the text's overall coherence?
Alternativas
Q3650827 Inglês
O texto seguinte servirá de base para responder à questão.

Big Data Begins to Crack the Case of Endometriosis

Records from millions of patients at University of California health centers found correlations between endometriosis, one of the most common diseases in women, and a bounty of other diseases.

By Levi Gadye

Scientists at UC San Francisco have found that endometriosis — a painful chronic disease that often goes undiagnosed yet is estimated to affect as many as 200 million women worldwide — frequently occurs alongside conditions like cancer, Crohn's disease, and migraine.

The research could improve diagnosis and, ultimately, treatments for endometriosis, preventing women from having to go on long diagnostic journeys in which they are told that nothing is wrong with them.

The study, which appeared in Cell Reports Medicine on July 31, used computational methods developed at UCSF to analyze anonymized patient records collected at the University of California's six health centers.

"We now have both the tools and the data to make a difference for the huge population that suffers from endometriosis," said Marina Sirota, PhD, the interim director of the UCSF Bakar Computational Health Sciences Institute (BCHSI), professor of pediatrics, and senior author of the paper. "We hope this can spur a sea change in how we approach this disorder."

"The impact on patients' lives is huge"

Endometriosis, often called 'endo,' occurs when the endometrium, the blood-rich tissue that grows in the uterus before being expelled each month during menstruation, spreads to other nearby organs. It causes chronic pain and infertility. It is estimated that nearly 10% of women worldwide suffer from it.

"Endo is extremely debilitating," said Linda Giudice, MD, PhD, MSc, a physician-scientist in the Department of Obstetrics, Gynecology and Reproductive Sciences at UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal relationships to being able to hold a job, have a family, and maintain psychological wellbeing."

The gold standard to diagnose endometriosis is surgery to find endometrial tissue outside of the uterus, and it is mainly treated with hormones to suppress the menstrual cycle, or surgery to remove the excess tissue.

But not everyone responds to hormonal therapy, which can have debilitating side effects. Even after surgery, the condition can flare up. Removal of the uterus is a last-ditch measure that is usually reserved for older women; but some women continue to experience pain even after a hysterectomy.

Giudice partnered with Sirota to leverage the UC health system's anonymized patient data against endo, which can vary dramatically across patients. Both Giudice and Sirota are principal investigators at the UCSF-Stanford Endometriosis Center for Discovery, Innovation, Training and Community Engagement (ENACT).

"This data is messy; it was not collected for research purposes but for the real, human purpose of helping women who need care," Sirota said. "We had the rare chance to rigorously assess how endometriosis presents across UCSF's patient population and then ask whether these observations held true with patients seen at the other UC health centers."

Data connects the dots for understanding endometriosis

Using algorithms developed for the task, Umair Khan, a bioinformatics graduate student in Sirota's lab and first author of the paper, hunted for connections linking endometriosis with the rest of each patient's health history.

He compared endo patients with patients who did not have it, and categorized the patients with endo into groups based on shared health histories. He mapped his findings from the UCSF data against the rest of the UC's health data to see if they held up across California.

"We found over 600 correlations between endometriosis and other conditions," Khan said. "These ranged from what we already knew or suspected, like infertility, autoimmune disease, and acid-reflux, to the unexpected, like certain cancers, asthma, and eye-related diseases."

Some patients had migraines, bolstering previous studies suggesting that migraine drugs might help treat endometriosis.

"In the past, studies like this would have been nearly impossible," said Tomiko Oskotsky, MD, an investigator at ENACT, associate professor in UCSF BCHSI, and co-author of the paper. "It was only 12 years ago that de-identified electronic health records became available at this scale."

The study supports the growing understanding of endometriosis as a "multi-system" disorder — a disease arising from dysfunction throughout the body.

"This is the kind of data we need to move the needle, which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually, we hope, tailored treatment for the millions of women who suffer from endometriosis."


https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case -endometriosis
From the statement "Endo is extremely debilitating," said Linda Giudice, what can be inferred about the author's perspective in including this quotation?
Alternativas
Q3650825 Inglês
O texto seguinte servirá de base para responder à questão.

Big Data Begins to Crack the Case of Endometriosis

Records from millions of patients at University of California health centers found correlations between endometriosis, one of the most common diseases in women, and a bounty of other diseases.

By Levi Gadye

Scientists at UC San Francisco have found that endometriosis — a painful chronic disease that often goes undiagnosed yet is estimated to affect as many as 200 million women worldwide — frequently occurs alongside conditions like cancer, Crohn's disease, and migraine.

The research could improve diagnosis and, ultimately, treatments for endometriosis, preventing women from having to go on long diagnostic journeys in which they are told that nothing is wrong with them.

The study, which appeared in Cell Reports Medicine on July 31, used computational methods developed at UCSF to analyze anonymized patient records collected at the University of California's six health centers.

"We now have both the tools and the data to make a difference for the huge population that suffers from endometriosis," said Marina Sirota, PhD, the interim director of the UCSF Bakar Computational Health Sciences Institute (BCHSI), professor of pediatrics, and senior author of the paper. "We hope this can spur a sea change in how we approach this disorder."

"The impact on patients' lives is huge"

Endometriosis, often called 'endo,' occurs when the endometrium, the blood-rich tissue that grows in the uterus before being expelled each month during menstruation, spreads to other nearby organs. It causes chronic pain and infertility. It is estimated that nearly 10% of women worldwide suffer from it.

"Endo is extremely debilitating," said Linda Giudice, MD, PhD, MSc, a physician-scientist in the Department of Obstetrics, Gynecology and Reproductive Sciences at UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal relationships to being able to hold a job, have a family, and maintain psychological wellbeing."

The gold standard to diagnose endometriosis is surgery to find endometrial tissue outside of the uterus, and it is mainly treated with hormones to suppress the menstrual cycle, or surgery to remove the excess tissue.

But not everyone responds to hormonal therapy, which can have debilitating side effects. Even after surgery, the condition can flare up. Removal of the uterus is a last-ditch measure that is usually reserved for older women; but some women continue to experience pain even after a hysterectomy.

Giudice partnered with Sirota to leverage the UC health system's anonymized patient data against endo, which can vary dramatically across patients. Both Giudice and Sirota are principal investigators at the UCSF-Stanford Endometriosis Center for Discovery, Innovation, Training and Community Engagement (ENACT).

"This data is messy; it was not collected for research purposes but for the real, human purpose of helping women who need care," Sirota said. "We had the rare chance to rigorously assess how endometriosis presents across UCSF's patient population and then ask whether these observations held true with patients seen at the other UC health centers."

Data connects the dots for understanding endometriosis

Using algorithms developed for the task, Umair Khan, a bioinformatics graduate student in Sirota's lab and first author of the paper, hunted for connections linking endometriosis with the rest of each patient's health history.

He compared endo patients with patients who did not have it, and categorized the patients with endo into groups based on shared health histories. He mapped his findings from the UCSF data against the rest of the UC's health data to see if they held up across California.

"We found over 600 correlations between endometriosis and other conditions," Khan said. "These ranged from what we already knew or suspected, like infertility, autoimmune disease, and acid-reflux, to the unexpected, like certain cancers, asthma, and eye-related diseases."

Some patients had migraines, bolstering previous studies suggesting that migraine drugs might help treat endometriosis.

"In the past, studies like this would have been nearly impossible," said Tomiko Oskotsky, MD, an investigator at ENACT, associate professor in UCSF BCHSI, and co-author of the paper. "It was only 12 years ago that de-identified electronic health records became available at this scale."

The study supports the growing understanding of endometriosis as a "multi-system" disorder — a disease arising from dysfunction throughout the body.

"This is the kind of data we need to move the needle, which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually, we hope, tailored treatment for the millions of women who suffer from endometriosis."


https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case -endometriosis
In the excerpt "This data is messy; it was not collected for research purposes but for the real, human purpose of helping women who need care", what does the pronoun "it" refer to?
Alternativas
Q3648798 Inglês

39.png (604×208)

For Better or For Worse, August 15th, 2025, Available at: https://www.gocomics.com/forbetterorforworse/2025/08/15


In panel 4, Laura thinks: “One thing about city kids… it doesn’t take much to make them happy!” The expression “city kid” most nearly means:
Alternativas
Q3648793 Inglês
The US may be a bitterly divided country, but I think I’ve found a topic which pretty much everyone can unite behind: tipping culture is out of control. The US norm of tipping at least 20% on a meal, and at (the very, very) least $1 a drink at a bar, has always confused European tourists. In recent years, however, tipping prompts have become so ubiquitous, have spread to so many new areas of commerce, that even Americans are confused about when and where a tip is appropriate. There is now almost no payment transaction in the US that doesn’t involve a prompt for a tip. If you go to get a coffee or pick up a takeout order, for example, an electronic screen will almost certainly get swivelled in your direction, asking if you want to add a 20%, 25% or 30% tip. More confusingly, however, if you go to the local convenience store to buy a pint of milk or a pack of crisps, chances are you’ll still see that tip screen pointed at you. You’re even prompted to leave a tip at some self-checkouts.
MAHDAWI, Arwa. Tipping culture in the US is out of control – we’re even asked to tip self-checkouts. The Guardian, 16 ago. 2023. Disponível em: https://www.theguardian.com Acesso em: 18 ago. 2025.
According to US cultural norms, what is generally considered appropriate tipping behavior?
Alternativas
Respostas
1421: B
1422: D
1423: A
1424: A
1425: D
1426: E
1427: E
1428: D
1429: B
1430: E
1431: C
1432: A
1433: C
1434: B
1435: A
1436: A
1437: B
1438: B
1439: A
1440: A