Questões de Concurso Público Prefeitura de Barra Bonita - SC 2026 para Professor II (Língua Estrangeira – Inglês)

Foram encontradas 12 questões

Q4392978 Inglês
O texto seguinte servirá de base para responder à questão.


A leader in the study of longevity is returning to UCLA Health


Renowned geroscientist and computational biologist Steve Horvath, PhD, is returning as a professor in the David Geffen School of Medicine at UCLA on July 1, after 4 1/2 years in the biotech industry. Previously, he was a full-time professor of Human Genetics and Biostatistics at UCLA for 22 years.

Geroscience is the modern term for the biology of aging. Dr. Horvath, who was born in Germany, is internationally known for his research into the aging process and, in particular, epigenetics, how the environment influences our genes, affecting a person's longevity.

His groundbreaking research, which he began at UCLA in 2011, looked at the "epigenetic age" of more than 13,000 DNA samples of people from the U.S. and Europe, determined from the chemical modifications of their DNA (also called DNA methylation).

People whose epigenetic age was higher than their chronological age were shown to be at an increased risk of death from all causes. From this, Dr. Horvath developed the "epigenetic clock," a way of measuring biological aging and mortality risk.

"The universal mammalian methylation clock was really a UCLA triumph — a true team effort," said Dr. Horvath, who received the 2026 Luminary Award at the Precision Medicine World Conference. That project, part of the international Mammalian Methylation Consortium that Dr. Horvath led, drew on collaborators across UCLA, including Jason Ernst, PhD; William Yang, MD, PhD; Ebru Erbay, MD, PhD; Karen Sears, PhD; and Ren Larison, PhD.

Aging is a growing field of study and the Division of Geriatrics is a research leader.

"Aging happens at the cellular level — every tissue in the human body shows signs of aging," explained Arun S. Karlamangla, MD, PhD, chief of the UCLA Division of Geriatrics. "The epigenetic profile is affected by stresses in life. As we age, these stresses change DNA functionality. Dr. Horvath's research showed that these changes can be quantified and used to predict a person's lifespan."

None of us has control over the DNA we're born with, but we do have some control over how long we live.

"The epigenetic clock is one window into biological aging, but it doesn't capture everything, and plenty of well-established factors influence how long and how well a person lives," said Dr. Horvath. "The strongest evidence is for the basics: not smoking, maintaining a healthy weight, a sensible diet, regular physical activity and good sleep."

Dr. Horvath has run the test on himself and by the epigenetic clock, he is about three years younger than his chronological age of 58.

New medications also show promise for improving longevity, he said. "There's active research interest in newer GLP-1 receptor agonists — e.g., the Ozempic/Wegovy class — which are reshaping how we think about metabolic health," said Dr. Horvath, adding that the same is true for anti-inflammatory and antifibrotic drugs.

Dr. Horvath's epigenetic clocks have become standard tools across aging research, used by teams worldwide to test what actually changes biological aging. 

They have been applied in the randomized DO-HEALTH trial, where omega-3, vitamin D and exercise modestly slowed epigenetic aging in adults older than 70; in the Women's Health Initiative, where faster epigenetic aging tracked with later cognitive impairment and dementia; and in studies of cardiovascular disease and mortality. This kind of population-level application aligns closely with the Division of Geriatrics' emphasis on healthy, independent life expectancy.

Dr. Horvath's research has also shown that the cells of different organs age at different rates. For instance, the liver ages faster than other organs, he said, particularly in the case of people with obesity.

Another discovery was that the blood and brain tissues of human males age faster than those of females, which might be the reason women live longer on average than men across all cultures and countries.

Leading in aging research

The study of aging at the UCLA Division of Geriatrics focuses on understanding the epidemiology of age-related conditions such as frailty, cognitive impairment and dementia, and improving the delivery of compassionate, comprehensive care to older adults.

Dr. Horvath's return to UCLA will bolster the department's role in aging research by translating his cellular research to clinical trials, said Dr. Karlamangla.

"We want to be pioneers in all three aspects: cellular research, clinical and population-level research, and health services and implementation research," Dr. Karlamangla said. "We are one of the pioneers in clinical innovation for the delivery of healthcare to older adults," he said, an approach that is called bench to bedside.

Life expectancy is important, but even more important is good health, which is necessary for independence, Dr. Karlamangla emphasized. This is referred to as healthy life expectancy, or independent life expectancy.

New work at UCLA

Along with serving as a professor, Dr. Horvath will return to UCLA Health as director of aging biology research in the Department of Medicine, working across 11 divisions. In this way, he will work directly with doctors to apply aging research to their patients. The move into the Department of Medicine is deliberate: his focus now is translating discoveries from aging biology into care for patients.
"What I'm most looking forward to in returning to UCLA is the people and the collaborative environment," said Dr. Horvath. "UCLA has remarkable strength across medicine, computational biology, stem cell biology, and the basic science of complex diseases, and being back in that setting with former colleagues and future students is what excites me most.

"It feels like the right place to do the next phase of this work: helping to translate findings from aging biology into the clinic."


https://www.uclahealth.org/news/article/leader-study-longevity-returning -ucla-health 
The article uses phrasal and prepositional expressions as well as discourse markers to establish relationships between ideas and avoid overly literal interpretation of individual words.

Judge the statements below as True (T) or False (F):

(__)In "From this, Dr. Horvath developed the 'epigenetic clock'", From this establishes a relationship between the preceding finding and the subsequent development.
(__)In "For instance, the liver ages faster than other organs", For instance introduces a specific example supporting the preceding general statement.
(__)In "Along with serving as a professor", Along with establishes a contrast between Dr. Horvath's academic position and his other institutional role.
(__)In "the project [...] drew on collaborators across UCLA", drew on means that the project made use of the expertise or contribution of those collaborators.

The correct sequence, from top to bottom, is: 
Alternativas
Q4392979 Inglês
O texto seguinte servirá de base para responder à questão.


A leader in the study of longevity is returning to UCLA Health


Renowned geroscientist and computational biologist Steve Horvath, PhD, is returning as a professor in the David Geffen School of Medicine at UCLA on July 1, after 4 1/2 years in the biotech industry. Previously, he was a full-time professor of Human Genetics and Biostatistics at UCLA for 22 years.

Geroscience is the modern term for the biology of aging. Dr. Horvath, who was born in Germany, is internationally known for his research into the aging process and, in particular, epigenetics, how the environment influences our genes, affecting a person's longevity.

His groundbreaking research, which he began at UCLA in 2011, looked at the "epigenetic age" of more than 13,000 DNA samples of people from the U.S. and Europe, determined from the chemical modifications of their DNA (also called DNA methylation).

People whose epigenetic age was higher than their chronological age were shown to be at an increased risk of death from all causes. From this, Dr. Horvath developed the "epigenetic clock," a way of measuring biological aging and mortality risk.

"The universal mammalian methylation clock was really a UCLA triumph — a true team effort," said Dr. Horvath, who received the 2026 Luminary Award at the Precision Medicine World Conference. That project, part of the international Mammalian Methylation Consortium that Dr. Horvath led, drew on collaborators across UCLA, including Jason Ernst, PhD; William Yang, MD, PhD; Ebru Erbay, MD, PhD; Karen Sears, PhD; and Ren Larison, PhD.

Aging is a growing field of study and the Division of Geriatrics is a research leader.

"Aging happens at the cellular level — every tissue in the human body shows signs of aging," explained Arun S. Karlamangla, MD, PhD, chief of the UCLA Division of Geriatrics. "The epigenetic profile is affected by stresses in life. As we age, these stresses change DNA functionality. Dr. Horvath's research showed that these changes can be quantified and used to predict a person's lifespan."

None of us has control over the DNA we're born with, but we do have some control over how long we live.

"The epigenetic clock is one window into biological aging, but it doesn't capture everything, and plenty of well-established factors influence how long and how well a person lives," said Dr. Horvath. "The strongest evidence is for the basics: not smoking, maintaining a healthy weight, a sensible diet, regular physical activity and good sleep."

Dr. Horvath has run the test on himself and by the epigenetic clock, he is about three years younger than his chronological age of 58.

New medications also show promise for improving longevity, he said. "There's active research interest in newer GLP-1 receptor agonists — e.g., the Ozempic/Wegovy class — which are reshaping how we think about metabolic health," said Dr. Horvath, adding that the same is true for anti-inflammatory and antifibrotic drugs.

Dr. Horvath's epigenetic clocks have become standard tools across aging research, used by teams worldwide to test what actually changes biological aging. 

They have been applied in the randomized DO-HEALTH trial, where omega-3, vitamin D and exercise modestly slowed epigenetic aging in adults older than 70; in the Women's Health Initiative, where faster epigenetic aging tracked with later cognitive impairment and dementia; and in studies of cardiovascular disease and mortality. This kind of population-level application aligns closely with the Division of Geriatrics' emphasis on healthy, independent life expectancy.

Dr. Horvath's research has also shown that the cells of different organs age at different rates. For instance, the liver ages faster than other organs, he said, particularly in the case of people with obesity.

Another discovery was that the blood and brain tissues of human males age faster than those of females, which might be the reason women live longer on average than men across all cultures and countries.

Leading in aging research

The study of aging at the UCLA Division of Geriatrics focuses on understanding the epidemiology of age-related conditions such as frailty, cognitive impairment and dementia, and improving the delivery of compassionate, comprehensive care to older adults.

Dr. Horvath's return to UCLA will bolster the department's role in aging research by translating his cellular research to clinical trials, said Dr. Karlamangla.

"We want to be pioneers in all three aspects: cellular research, clinical and population-level research, and health services and implementation research," Dr. Karlamangla said. "We are one of the pioneers in clinical innovation for the delivery of healthcare to older adults," he said, an approach that is called bench to bedside.

Life expectancy is important, but even more important is good health, which is necessary for independence, Dr. Karlamangla emphasized. This is referred to as healthy life expectancy, or independent life expectancy.

New work at UCLA

Along with serving as a professor, Dr. Horvath will return to UCLA Health as director of aging biology research in the Department of Medicine, working across 11 divisions. In this way, he will work directly with doctors to apply aging research to their patients. The move into the Department of Medicine is deliberate: his focus now is translating discoveries from aging biology into care for patients.
"What I'm most looking forward to in returning to UCLA is the people and the collaborative environment," said Dr. Horvath. "UCLA has remarkable strength across medicine, computational biology, stem cell biology, and the basic science of complex diseases, and being back in that setting with former colleagues and future students is what excites me most.

"It feels like the right place to do the next phase of this work: helping to translate findings from aging biology into the clinic."


https://www.uclahealth.org/news/article/leader-study-longevity-returning -ucla-health 
The article uses reference chains to connect research tools, studies and conclusions across sentences. Consider the following passage:

"Dr. Horvath's epigenetic clocks have become standard tools across aging research [...]. They have been applied in the randomized DO-HEALTH trial [...] and in the Women's Health Initiative [...]. This kind of population-level application aligns closely with the Division of Geriatrics' emphasis on healthy, independent life expectancy."

Considering textual cohesion, select the correct alternative.
Alternativas
Q4392982 Inglês
O texto seguinte servirá de base para responder à questão.


A leader in the study of longevity is returning to UCLA Health


Renowned geroscientist and computational biologist Steve Horvath, PhD, is returning as a professor in the David Geffen School of Medicine at UCLA on July 1, after 4 1/2 years in the biotech industry. Previously, he was a full-time professor of Human Genetics and Biostatistics at UCLA for 22 years.

Geroscience is the modern term for the biology of aging. Dr. Horvath, who was born in Germany, is internationally known for his research into the aging process and, in particular, epigenetics, how the environment influences our genes, affecting a person's longevity.

His groundbreaking research, which he began at UCLA in 2011, looked at the "epigenetic age" of more than 13,000 DNA samples of people from the U.S. and Europe, determined from the chemical modifications of their DNA (also called DNA methylation).

People whose epigenetic age was higher than their chronological age were shown to be at an increased risk of death from all causes. From this, Dr. Horvath developed the "epigenetic clock," a way of measuring biological aging and mortality risk.

"The universal mammalian methylation clock was really a UCLA triumph — a true team effort," said Dr. Horvath, who received the 2026 Luminary Award at the Precision Medicine World Conference. That project, part of the international Mammalian Methylation Consortium that Dr. Horvath led, drew on collaborators across UCLA, including Jason Ernst, PhD; William Yang, MD, PhD; Ebru Erbay, MD, PhD; Karen Sears, PhD; and Ren Larison, PhD.

Aging is a growing field of study and the Division of Geriatrics is a research leader.

"Aging happens at the cellular level — every tissue in the human body shows signs of aging," explained Arun S. Karlamangla, MD, PhD, chief of the UCLA Division of Geriatrics. "The epigenetic profile is affected by stresses in life. As we age, these stresses change DNA functionality. Dr. Horvath's research showed that these changes can be quantified and used to predict a person's lifespan."

None of us has control over the DNA we're born with, but we do have some control over how long we live.

"The epigenetic clock is one window into biological aging, but it doesn't capture everything, and plenty of well-established factors influence how long and how well a person lives," said Dr. Horvath. "The strongest evidence is for the basics: not smoking, maintaining a healthy weight, a sensible diet, regular physical activity and good sleep."

Dr. Horvath has run the test on himself and by the epigenetic clock, he is about three years younger than his chronological age of 58.

New medications also show promise for improving longevity, he said. "There's active research interest in newer GLP-1 receptor agonists — e.g., the Ozempic/Wegovy class — which are reshaping how we think about metabolic health," said Dr. Horvath, adding that the same is true for anti-inflammatory and antifibrotic drugs.

Dr. Horvath's epigenetic clocks have become standard tools across aging research, used by teams worldwide to test what actually changes biological aging. 

They have been applied in the randomized DO-HEALTH trial, where omega-3, vitamin D and exercise modestly slowed epigenetic aging in adults older than 70; in the Women's Health Initiative, where faster epigenetic aging tracked with later cognitive impairment and dementia; and in studies of cardiovascular disease and mortality. This kind of population-level application aligns closely with the Division of Geriatrics' emphasis on healthy, independent life expectancy.

Dr. Horvath's research has also shown that the cells of different organs age at different rates. For instance, the liver ages faster than other organs, he said, particularly in the case of people with obesity.

Another discovery was that the blood and brain tissues of human males age faster than those of females, which might be the reason women live longer on average than men across all cultures and countries.

Leading in aging research

The study of aging at the UCLA Division of Geriatrics focuses on understanding the epidemiology of age-related conditions such as frailty, cognitive impairment and dementia, and improving the delivery of compassionate, comprehensive care to older adults.

Dr. Horvath's return to UCLA will bolster the department's role in aging research by translating his cellular research to clinical trials, said Dr. Karlamangla.

"We want to be pioneers in all three aspects: cellular research, clinical and population-level research, and health services and implementation research," Dr. Karlamangla said. "We are one of the pioneers in clinical innovation for the delivery of healthcare to older adults," he said, an approach that is called bench to bedside.

Life expectancy is important, but even more important is good health, which is necessary for independence, Dr. Karlamangla emphasized. This is referred to as healthy life expectancy, or independent life expectancy.

New work at UCLA

Along with serving as a professor, Dr. Horvath will return to UCLA Health as director of aging biology research in the Department of Medicine, working across 11 divisions. In this way, he will work directly with doctors to apply aging research to their patients. The move into the Department of Medicine is deliberate: his focus now is translating discoveries from aging biology into care for patients.
"What I'm most looking forward to in returning to UCLA is the people and the collaborative environment," said Dr. Horvath. "UCLA has remarkable strength across medicine, computational biology, stem cell biology, and the basic science of complex diseases, and being back in that setting with former colleagues and future students is what excites me most.

"It feels like the right place to do the next phase of this work: helping to translate findings from aging biology into the clinic."


https://www.uclahealth.org/news/article/leader-study-longevity-returning -ucla-health 
A public-school English teacher uses the UCLA Health article to assess whether students can distinguish established findings from hypotheses and emerging possibilities. Such distinctions depend on close reading of lexical choices that indicate different degrees of certainty.

Based on the text, judge the statements below as True (T) or False (F):

(__)The epigenetic clock is presented as one useful measure of biological aging rather than as a complete explanation of longevity.
(__)The text establishes as a demonstrated causal fact that faster aging of male blood and brain tissues explains the difference in life expectancy between men and women.
(__)Lifestyle practices such as physical activity, adequate sleep and not smoking are presented as supported by stronger evidence than the newer medications discussed.
(__)The expression "bench to bedside" describes a movement from clinical observations toward laboratory research without direct application to patient care.

The correct sequence, from top to bottom, is: 
Alternativas
Q4392983 Inglês
O texto seguinte servirá de base para responder à questão.


A leader in the study of longevity is returning to UCLA Health


Renowned geroscientist and computational biologist Steve Horvath, PhD, is returning as a professor in the David Geffen School of Medicine at UCLA on July 1, after 4 1/2 years in the biotech industry. Previously, he was a full-time professor of Human Genetics and Biostatistics at UCLA for 22 years.

Geroscience is the modern term for the biology of aging. Dr. Horvath, who was born in Germany, is internationally known for his research into the aging process and, in particular, epigenetics, how the environment influences our genes, affecting a person's longevity.

His groundbreaking research, which he began at UCLA in 2011, looked at the "epigenetic age" of more than 13,000 DNA samples of people from the U.S. and Europe, determined from the chemical modifications of their DNA (also called DNA methylation).

People whose epigenetic age was higher than their chronological age were shown to be at an increased risk of death from all causes. From this, Dr. Horvath developed the "epigenetic clock," a way of measuring biological aging and mortality risk.

"The universal mammalian methylation clock was really a UCLA triumph — a true team effort," said Dr. Horvath, who received the 2026 Luminary Award at the Precision Medicine World Conference. That project, part of the international Mammalian Methylation Consortium that Dr. Horvath led, drew on collaborators across UCLA, including Jason Ernst, PhD; William Yang, MD, PhD; Ebru Erbay, MD, PhD; Karen Sears, PhD; and Ren Larison, PhD.

Aging is a growing field of study and the Division of Geriatrics is a research leader.

"Aging happens at the cellular level — every tissue in the human body shows signs of aging," explained Arun S. Karlamangla, MD, PhD, chief of the UCLA Division of Geriatrics. "The epigenetic profile is affected by stresses in life. As we age, these stresses change DNA functionality. Dr. Horvath's research showed that these changes can be quantified and used to predict a person's lifespan."

None of us has control over the DNA we're born with, but we do have some control over how long we live.

"The epigenetic clock is one window into biological aging, but it doesn't capture everything, and plenty of well-established factors influence how long and how well a person lives," said Dr. Horvath. "The strongest evidence is for the basics: not smoking, maintaining a healthy weight, a sensible diet, regular physical activity and good sleep."

Dr. Horvath has run the test on himself and by the epigenetic clock, he is about three years younger than his chronological age of 58.

New medications also show promise for improving longevity, he said. "There's active research interest in newer GLP-1 receptor agonists — e.g., the Ozempic/Wegovy class — which are reshaping how we think about metabolic health," said Dr. Horvath, adding that the same is true for anti-inflammatory and antifibrotic drugs.

Dr. Horvath's epigenetic clocks have become standard tools across aging research, used by teams worldwide to test what actually changes biological aging. 

They have been applied in the randomized DO-HEALTH trial, where omega-3, vitamin D and exercise modestly slowed epigenetic aging in adults older than 70; in the Women's Health Initiative, where faster epigenetic aging tracked with later cognitive impairment and dementia; and in studies of cardiovascular disease and mortality. This kind of population-level application aligns closely with the Division of Geriatrics' emphasis on healthy, independent life expectancy.

Dr. Horvath's research has also shown that the cells of different organs age at different rates. For instance, the liver ages faster than other organs, he said, particularly in the case of people with obesity.

Another discovery was that the blood and brain tissues of human males age faster than those of females, which might be the reason women live longer on average than men across all cultures and countries.

Leading in aging research

The study of aging at the UCLA Division of Geriatrics focuses on understanding the epidemiology of age-related conditions such as frailty, cognitive impairment and dementia, and improving the delivery of compassionate, comprehensive care to older adults.

Dr. Horvath's return to UCLA will bolster the department's role in aging research by translating his cellular research to clinical trials, said Dr. Karlamangla.

"We want to be pioneers in all three aspects: cellular research, clinical and population-level research, and health services and implementation research," Dr. Karlamangla said. "We are one of the pioneers in clinical innovation for the delivery of healthcare to older adults," he said, an approach that is called bench to bedside.

Life expectancy is important, but even more important is good health, which is necessary for independence, Dr. Karlamangla emphasized. This is referred to as healthy life expectancy, or independent life expectancy.

New work at UCLA

Along with serving as a professor, Dr. Horvath will return to UCLA Health as director of aging biology research in the Department of Medicine, working across 11 divisions. In this way, he will work directly with doctors to apply aging research to their patients. The move into the Department of Medicine is deliberate: his focus now is translating discoveries from aging biology into care for patients.
"What I'm most looking forward to in returning to UCLA is the people and the collaborative environment," said Dr. Horvath. "UCLA has remarkable strength across medicine, computational biology, stem cell biology, and the basic science of complex diseases, and being back in that setting with former colleagues and future students is what excites me most.

"It feels like the right place to do the next phase of this work: helping to translate findings from aging biology into the clinic."


https://www.uclahealth.org/news/article/leader-study-longevity-returning -ucla-health 
A public-school teacher uses the article to design tasks that require different reading strategies, from locating information to examining how scientific claims are framed and supported.

Judge the statements below as True (T) or False (F):

(__)Reading the title, section headings and opening paragraphs rapidly to identify the article's general focus is consistent with skimming.
(__)Searching the article specifically for figures such as "13,000 DNA samples", "58" and "11 divisions" is an example of scanning.
(__)Concluding that the article proves newer medications extend human lifespan is a valid inference because the expression "show promise" presents their effectiveness as established.
(__)Examining how the institutional source presents UCLA's research achievements and comparing promotional framing with the strength of the evidence is compatible with critical literacy.

The correct sequence, from top to bottom, is:
Alternativas
Q4392984 Inglês
O texto seguinte servirá de base para responder à questão.


A leader in the study of longevity is returning to UCLA Health


Renowned geroscientist and computational biologist Steve Horvath, PhD, is returning as a professor in the David Geffen School of Medicine at UCLA on July 1, after 4 1/2 years in the biotech industry. Previously, he was a full-time professor of Human Genetics and Biostatistics at UCLA for 22 years.

Geroscience is the modern term for the biology of aging. Dr. Horvath, who was born in Germany, is internationally known for his research into the aging process and, in particular, epigenetics, how the environment influences our genes, affecting a person's longevity.

His groundbreaking research, which he began at UCLA in 2011, looked at the "epigenetic age" of more than 13,000 DNA samples of people from the U.S. and Europe, determined from the chemical modifications of their DNA (also called DNA methylation).

People whose epigenetic age was higher than their chronological age were shown to be at an increased risk of death from all causes. From this, Dr. Horvath developed the "epigenetic clock," a way of measuring biological aging and mortality risk.

"The universal mammalian methylation clock was really a UCLA triumph — a true team effort," said Dr. Horvath, who received the 2026 Luminary Award at the Precision Medicine World Conference. That project, part of the international Mammalian Methylation Consortium that Dr. Horvath led, drew on collaborators across UCLA, including Jason Ernst, PhD; William Yang, MD, PhD; Ebru Erbay, MD, PhD; Karen Sears, PhD; and Ren Larison, PhD.

Aging is a growing field of study and the Division of Geriatrics is a research leader.

"Aging happens at the cellular level — every tissue in the human body shows signs of aging," explained Arun S. Karlamangla, MD, PhD, chief of the UCLA Division of Geriatrics. "The epigenetic profile is affected by stresses in life. As we age, these stresses change DNA functionality. Dr. Horvath's research showed that these changes can be quantified and used to predict a person's lifespan."

None of us has control over the DNA we're born with, but we do have some control over how long we live.

"The epigenetic clock is one window into biological aging, but it doesn't capture everything, and plenty of well-established factors influence how long and how well a person lives," said Dr. Horvath. "The strongest evidence is for the basics: not smoking, maintaining a healthy weight, a sensible diet, regular physical activity and good sleep."

Dr. Horvath has run the test on himself and by the epigenetic clock, he is about three years younger than his chronological age of 58.

New medications also show promise for improving longevity, he said. "There's active research interest in newer GLP-1 receptor agonists — e.g., the Ozempic/Wegovy class — which are reshaping how we think about metabolic health," said Dr. Horvath, adding that the same is true for anti-inflammatory and antifibrotic drugs.

Dr. Horvath's epigenetic clocks have become standard tools across aging research, used by teams worldwide to test what actually changes biological aging. 

They have been applied in the randomized DO-HEALTH trial, where omega-3, vitamin D and exercise modestly slowed epigenetic aging in adults older than 70; in the Women's Health Initiative, where faster epigenetic aging tracked with later cognitive impairment and dementia; and in studies of cardiovascular disease and mortality. This kind of population-level application aligns closely with the Division of Geriatrics' emphasis on healthy, independent life expectancy.

Dr. Horvath's research has also shown that the cells of different organs age at different rates. For instance, the liver ages faster than other organs, he said, particularly in the case of people with obesity.

Another discovery was that the blood and brain tissues of human males age faster than those of females, which might be the reason women live longer on average than men across all cultures and countries.

Leading in aging research

The study of aging at the UCLA Division of Geriatrics focuses on understanding the epidemiology of age-related conditions such as frailty, cognitive impairment and dementia, and improving the delivery of compassionate, comprehensive care to older adults.

Dr. Horvath's return to UCLA will bolster the department's role in aging research by translating his cellular research to clinical trials, said Dr. Karlamangla.

"We want to be pioneers in all three aspects: cellular research, clinical and population-level research, and health services and implementation research," Dr. Karlamangla said. "We are one of the pioneers in clinical innovation for the delivery of healthcare to older adults," he said, an approach that is called bench to bedside.

Life expectancy is important, but even more important is good health, which is necessary for independence, Dr. Karlamangla emphasized. This is referred to as healthy life expectancy, or independent life expectancy.

New work at UCLA

Along with serving as a professor, Dr. Horvath will return to UCLA Health as director of aging biology research in the Department of Medicine, working across 11 divisions. In this way, he will work directly with doctors to apply aging research to their patients. The move into the Department of Medicine is deliberate: his focus now is translating discoveries from aging biology into care for patients.
"What I'm most looking forward to in returning to UCLA is the people and the collaborative environment," said Dr. Horvath. "UCLA has remarkable strength across medicine, computational biology, stem cell biology, and the basic science of complex diseases, and being back in that setting with former colleagues and future students is what excites me most.

"It feels like the right place to do the next phase of this work: helping to translate findings from aging biology into the clinic."


https://www.uclahealth.org/news/article/leader-study-longevity-returning -ucla-health 
The article combines tense, voice and modality to distinguish current relevance, research findings and degrees of epistemic certainty. Consider the grammatical choices made in the excerpts below.

Analyze the statements:

I.In "Dr. Horvath's epigenetic clocks have become standard tools across aging research", the Present Perfect relates a development originating in the past to a current state.
II.In "People whose epigenetic age was higher [...] were shown to be at an increased risk", the passive construction foregrounds the research finding rather than the researchers responsible for demonstrating it.
III.In "which might be the reason women live longer", the modal verb might presents the proposed explanation as a conclusion regarded by the writer as highly certain.

It is correct to state that:
Alternativas
Q4392986 Inglês
O texto seguinte servirá de base para responder à questão.


A leader in the study of longevity is returning to UCLA Health


Renowned geroscientist and computational biologist Steve Horvath, PhD, is returning as a professor in the David Geffen School of Medicine at UCLA on July 1, after 4 1/2 years in the biotech industry. Previously, he was a full-time professor of Human Genetics and Biostatistics at UCLA for 22 years.

Geroscience is the modern term for the biology of aging. Dr. Horvath, who was born in Germany, is internationally known for his research into the aging process and, in particular, epigenetics, how the environment influences our genes, affecting a person's longevity.

His groundbreaking research, which he began at UCLA in 2011, looked at the "epigenetic age" of more than 13,000 DNA samples of people from the U.S. and Europe, determined from the chemical modifications of their DNA (also called DNA methylation).

People whose epigenetic age was higher than their chronological age were shown to be at an increased risk of death from all causes. From this, Dr. Horvath developed the "epigenetic clock," a way of measuring biological aging and mortality risk.

"The universal mammalian methylation clock was really a UCLA triumph — a true team effort," said Dr. Horvath, who received the 2026 Luminary Award at the Precision Medicine World Conference. That project, part of the international Mammalian Methylation Consortium that Dr. Horvath led, drew on collaborators across UCLA, including Jason Ernst, PhD; William Yang, MD, PhD; Ebru Erbay, MD, PhD; Karen Sears, PhD; and Ren Larison, PhD.

Aging is a growing field of study and the Division of Geriatrics is a research leader.

"Aging happens at the cellular level — every tissue in the human body shows signs of aging," explained Arun S. Karlamangla, MD, PhD, chief of the UCLA Division of Geriatrics. "The epigenetic profile is affected by stresses in life. As we age, these stresses change DNA functionality. Dr. Horvath's research showed that these changes can be quantified and used to predict a person's lifespan."

None of us has control over the DNA we're born with, but we do have some control over how long we live.

"The epigenetic clock is one window into biological aging, but it doesn't capture everything, and plenty of well-established factors influence how long and how well a person lives," said Dr. Horvath. "The strongest evidence is for the basics: not smoking, maintaining a healthy weight, a sensible diet, regular physical activity and good sleep."

Dr. Horvath has run the test on himself and by the epigenetic clock, he is about three years younger than his chronological age of 58.

New medications also show promise for improving longevity, he said. "There's active research interest in newer GLP-1 receptor agonists — e.g., the Ozempic/Wegovy class — which are reshaping how we think about metabolic health," said Dr. Horvath, adding that the same is true for anti-inflammatory and antifibrotic drugs.

Dr. Horvath's epigenetic clocks have become standard tools across aging research, used by teams worldwide to test what actually changes biological aging. 

They have been applied in the randomized DO-HEALTH trial, where omega-3, vitamin D and exercise modestly slowed epigenetic aging in adults older than 70; in the Women's Health Initiative, where faster epigenetic aging tracked with later cognitive impairment and dementia; and in studies of cardiovascular disease and mortality. This kind of population-level application aligns closely with the Division of Geriatrics' emphasis on healthy, independent life expectancy.

Dr. Horvath's research has also shown that the cells of different organs age at different rates. For instance, the liver ages faster than other organs, he said, particularly in the case of people with obesity.

Another discovery was that the blood and brain tissues of human males age faster than those of females, which might be the reason women live longer on average than men across all cultures and countries.

Leading in aging research

The study of aging at the UCLA Division of Geriatrics focuses on understanding the epidemiology of age-related conditions such as frailty, cognitive impairment and dementia, and improving the delivery of compassionate, comprehensive care to older adults.

Dr. Horvath's return to UCLA will bolster the department's role in aging research by translating his cellular research to clinical trials, said Dr. Karlamangla.

"We want to be pioneers in all three aspects: cellular research, clinical and population-level research, and health services and implementation research," Dr. Karlamangla said. "We are one of the pioneers in clinical innovation for the delivery of healthcare to older adults," he said, an approach that is called bench to bedside.

Life expectancy is important, but even more important is good health, which is necessary for independence, Dr. Karlamangla emphasized. This is referred to as healthy life expectancy, or independent life expectancy.

New work at UCLA

Along with serving as a professor, Dr. Horvath will return to UCLA Health as director of aging biology research in the Department of Medicine, working across 11 divisions. In this way, he will work directly with doctors to apply aging research to their patients. The move into the Department of Medicine is deliberate: his focus now is translating discoveries from aging biology into care for patients.
"What I'm most looking forward to in returning to UCLA is the people and the collaborative environment," said Dr. Horvath. "UCLA has remarkable strength across medicine, computational biology, stem cell biology, and the basic science of complex diseases, and being back in that setting with former colleagues and future students is what excites me most.

"It feels like the right place to do the next phase of this work: helping to translate findings from aging biology into the clinic."


https://www.uclahealth.org/news/article/leader-study-longevity-returning -ucla-health 
A public-school English teacher uses the UCLA Health article to design a sequence of reading tasks. In the first stage, students identify explicit information about Dr. Horvath's career and research. In the second, they distinguish established evidence from tentative claims by examining expressions such as "show promise" and "might be the reason". In the final stage, they produce a clear summary of the article, selecting relevant evidence and preserving the degree of certainty expressed in the original text.

Considering the CEFR (Common European Framework of Reference for Languages) as a framework for progression in communicative language ability, select the correct alternative.
Alternativas
Q4392987 Inglês
In natural spoken English, words are not necessarily pronounced in exactly the same way as when they are produced in isolation. Connected speech may involve changes related to linking, sound omission, stress placement and the interaction between adjacent sounds.

Judge the statements below as True (T) or False (F):

(__)In a non-rhotic variety of British English, the final letter r in far is normally silent when the word occurs alone, but the corresponding sound may be pronounced in far away because the following word begins with a vowel.
(__)In rapid speech, the t sound in next day may be omitted because of the complex consonant sequence, illustrating elision rather than the addition of a new sound.
(__)In did you, the final sound of did and the initial sound represented by y in you may interact and produce a pronunciation similar to the beginning of the word June.
(__)The words photograph and photography maintain primary stress on the same syllable because words belonging to the same lexical family normally preserve identical stress patterns.

The correct sequence, from top to bottom, is: 
Alternativas
Q4392988 Inglês
An English teacher notices that advanced students frequently produce grammatically possible sentences that sound non-idiomatic because they combine words in unusual ways. The teacher decides to redesign part of the course according to principles associated with the Lexical Approach.

Select the classroom practice that is most consistent with this approach.
Alternativas
Q4392989 Inglês
Connected speech may involve phonological processes that are not evident from the orthographic form of isolated words. Consider common descriptions of English pronunciation in fluent speech.

Judge the statements below as True (T) or False (F):

(__)In a non-rhotic accent, far away may contain a linking /r/ even though word-final /r/ would not normally be pronounced before a pause.
(__)In ten people, /n/ may be realized with a bilabial place of articulation before /p/, illustrating anticipatory assimilation.
(__)When /t/ is omitted from a cluster in a rapid pronunciation of next day, the process is properly classified as epenthesis.
(__)In connected speech, the sequence /d/ + /j/ in would you may undergo coalescence and be realized with a sound resembling /dʒ/.

The correct sequence, from top to bottom, is:
Alternativas
Q4392991 Inglês
Advanced grammatical competence requires recognizing syntactic relationships that remain equivalent even when surface structures differ.

Analyze the statements below:

I.Had the committee known about the procedural error, it would have postponed the vote is an inverted third conditional corresponding to If the committee had known about the procedural error....
II.She asked where did the students go preserves the appropriate word order of an indirect interrogative clause in standard English.
III.If he had accepted the position, he would be working here now combines a counterfactual past condition with a hypothetical present consequence.

It is correct to state that:
Alternativas
Q4392996 Inglês
The treatment of English as a lingua franca in the BNCC affects both the understanding of linguistic variation and the relationship among the different dimensions of language learning. 

Analyze the statements below:

I.Treating English as a lingua franca challenges the idea that legitimate use of the language belongs exclusively to speakers from particular national territories.
II.Linguistic knowledge should be mastered before oral, reading and writing practices, since the BNCC treats grammatical knowledge as a prerequisite for meaningful language use.
III.The intercultural dimension includes reflection on relations among language, identity and culture and on the social effects associated with the global circulation of English.

It is correct to state that:
Alternativas
Q4392997 Inglês
Read the study case:

A public-school English teacher wants to work within Communicative Language Teaching but rejects the idea that communicative teaching requires the complete exclusion of explicit attention to linguistic form. The class objective is to develop students' ability to negotiate information while maintaining sufficient accuracy for successful communication.

Considering Communicative Language Teaching (CLT), select the correct pedagogical arrangement.
Alternativas
Respostas
1: C
2: B
3: A
4: D
5: B
6: D
7: C
8: C
9: A
10: D
11: D
12: B