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Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650837
Inglês
During a training session on text genres, teachers were
asked to point out an example that clearly represents a
written academic text genre commonly used in education.
Which option is correct?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650836
Inglês
Complete the sentence with the appropriate prepositions:
She is interested ___ learning new languages, focused ___ improving her pronunciation, and proud ___ her progress so far.
Select the correct option.
She is interested ___ learning new languages, focused ___ improving her pronunciation, and proud ___ her progress so far.
Select the correct option.
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650835
Inglês
In a classroom discussion about different types of nouns,
the teacher asked students to identify which group
contains only abstract nouns. Which option should they
choose?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650834
Inglês
In academic English, phrasal verbs often carry meanings
that go beyond the literal combination of verb and
preposition, demanding contextual interpretation.
Observe the sentence below:
"Despite the unexpected technical problems during the presentation, the team managed to ___ the challenges and deliver the project on time."
Which option correctly completes the sentence with the most appropriate phrasal verb?
Observe the sentence below:
"Despite the unexpected technical problems during the presentation, the team managed to ___ the challenges and deliver the project on time."
Which option correctly completes the sentence with the most appropriate phrasal verb?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650833
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
Which connector in the sentence "The research could
improve diagnosis and, ultimately, treatments for
endometriosis" indicates a relation of finality/goal?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650832
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
Considering the final section of the text, where Giudice
states "We're finally getting closer to faster diagnosis
and, eventually, tailored treatment for the millions of
women who suffer from endometriosis", what does this
conclusion primarily contribute to the text's coherence?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650831
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
In the paragraph beginning with "This data is messy; it
was not collected for research purposes but for the real,
human purpose of helping women who need care", which
cohesive device connects the idea of limitation with
contrast?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650830
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
Which sentence correctly identifies the verb tense in the
clause "We hope this can spur a sea change in how we
approach this disorder"?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650829
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
In the passage "The research could improve diagnosis
and, ultimately, treatments for endometriosis, preventing
women from having to go on long diagnostic journeys in
which they are told that nothing is wrong with them", what
is the main purpose of this sentence within the text's
overall coherence?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650828
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
In the excerpt "Endometriosis, often called 'endo,' occurs
when the endometrium spreads to other nearby organs",
how does the adverb "often" contribute to meaning?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650827
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
From the statement "Endo is extremely debilitating," said
Linda Giudice, what can be inferred about the author's
perspective in including this quotation?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650826
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
In the excerpt "The gold standard to diagnose
endometriosis is surgery to find endometrial tissue
outside of the uterus", which voice is the verb "is" in?
Ano: 2025
Banca:
AMAUC
Órgão:
Prefeitura de Piratuba - SC
Prova:
AMAUC - 2025 - Prefeitura de Piratuba - SC - Professor Inglês |
Q3650825
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Big Data Begins to Crack the Case of Endometriosis
Records from millions of patients at University of
California health centers found correlations between
endometriosis, one of the most common diseases in
women, and a bounty of other diseases.
By Levi Gadye
Scientists at UC San Francisco have found that
endometriosis — a painful chronic disease that often
goes undiagnosed yet is estimated to affect as many as
200 million women worldwide — frequently occurs
alongside conditions like cancer, Crohn's disease, and
migraine.
The research could improve diagnosis and, ultimately,
treatments for endometriosis, preventing women from
having to go on long diagnostic journeys in which they
are told that nothing is wrong with them.
The study, which appeared in Cell Reports Medicine on
July 31, used computational methods developed at
UCSF to analyze anonymized patient records collected at
the University of California's six health centers.
"We now have both the tools and the data to make a
difference for the huge population that suffers from
endometriosis," said Marina Sirota, PhD, the interim
director of the UCSF Bakar Computational Health
Sciences Institute (BCHSI), professor of pediatrics, and
senior author of the paper. "We hope this can spur a sea
change in how we approach this disorder."
"The impact on patients' lives is huge"
Endometriosis, often called 'endo,' occurs when the
endometrium, the blood-rich tissue that grows in the
uterus before being expelled each month during
menstruation, spreads to other nearby organs. It causes
chronic pain and infertility. It is estimated that nearly 10%
of women worldwide suffer from it.
"Endo is extremely debilitating," said Linda Giudice, MD,
PhD, MSc, a physician-scientist in the Department of
Obstetrics, Gynecology and Reproductive Sciences at
UCSF and co-author of the paper. "The impact on patients' lives is huge, from their interpersonal
relationships to being able to hold a job, have a family,
and maintain psychological wellbeing."
The gold standard to diagnose endometriosis is surgery
to find endometrial tissue outside of the uterus, and it is
mainly treated with hormones to suppress the menstrual
cycle, or surgery to remove the excess tissue.
But not everyone responds to hormonal therapy, which
can have debilitating side effects. Even after surgery, the
condition can flare up. Removal of the uterus is a
last-ditch measure that is usually reserved for older
women; but some women continue to experience pain
even after a hysterectomy.
Giudice partnered with Sirota to leverage the UC health
system's anonymized patient data against endo, which
can vary dramatically across patients. Both Giudice and
Sirota are principal investigators at the UCSF-Stanford
Endometriosis Center for Discovery, Innovation, Training
and Community Engagement (ENACT).
"This data is messy; it was not collected for research
purposes but for the real, human purpose of helping
women who need care," Sirota said. "We had the rare
chance to rigorously assess how endometriosis presents
across UCSF's patient population and then ask whether
these observations held true with patients seen at the
other UC health centers."
Data connects the dots for understanding endometriosis
Using algorithms developed for the task, Umair Khan, a
bioinformatics graduate student in Sirota's lab and first
author of the paper, hunted for connections linking
endometriosis with the rest of each patient's health
history.
He compared endo patients with patients who did not
have it, and categorized the patients with endo into
groups based on shared health histories. He mapped his
findings from the UCSF data against the rest of the UC's
health data to see if they held up across California.
"We found over 600 correlations between endometriosis
and other conditions," Khan said. "These ranged from
what we already knew or suspected, like infertility,
autoimmune disease, and acid-reflux, to the unexpected,
like certain cancers, asthma, and eye-related diseases."
Some patients had migraines, bolstering previous studies
suggesting that migraine drugs might help treat
endometriosis.
"In the past, studies like this would have been nearly
impossible," said Tomiko Oskotsky, MD, an investigator
at ENACT, associate professor in UCSF BCHSI, and
co-author of the paper. "It was only 12 years ago that
de-identified electronic health records became available
at this scale."
The study supports the growing understanding of
endometriosis as a "multi-system" disorder — a disease
arising from dysfunction throughout the body.
"This is the kind of data we need to move the needle,
which hasn't moved in decades," Giudice said. "We're finally getting closer to faster diagnosis and, eventually,
we hope, tailored treatment for the millions of women
who suffer from endometriosis."
https://www.ucsf.edu/news/2025/07/430471/big-data-begins-crack-case
-endometriosis
In the excerpt "This data is messy; it was not collected for
research purposes but for the real, human purpose of
helping women who need care", what does the pronoun
"it" refer to?
Ano: 2025
Banca:
AMEOSC
Órgão:
Prefeitura de São Miguel do Oeste - SC
Prova:
AMEOSC - 2025 - Prefeitura de São Miguel do Oeste - SC - Professor de Língua Inglesa |
Q3643970
Inglês
Examine this morphological breakdown:
"The unhappiness of the restructured employees was predictable."
How many bound morphemes are present in this sentence?
"The unhappiness of the restructured employees was predictable."
How many bound morphemes are present in this sentence?
Ano: 2025
Banca:
AMEOSC
Órgão:
Prefeitura de São Miguel do Oeste - SC
Prova:
AMEOSC - 2025 - Prefeitura de São Miguel do Oeste - SC - Professor de Língua Inglesa |
Q3643969
Inglês
Identify the syntactic structure of this sentence:
"Although the research team had anticipated positive results, the data revealed significant anomalies that challenged their initial hypothesis."
This sentence exemplifies:
"Although the research team had anticipated positive results, the data revealed significant anomalies that challenged their initial hypothesis."
This sentence exemplifies:
Ano: 2025
Banca:
AMEOSC
Órgão:
Prefeitura de São Miguel do Oeste - SC
Prova:
AMEOSC - 2025 - Prefeitura de São Miguel do Oeste - SC - Professor de Língua Inglesa |
Q3643968
Inglês
Literary and non-literary texts serve different purposes. A
short story is typically fictional and may rely on literary
devices such as symbolism and metaphor to convey
meaning. On the other hand, a newspaper article aims to
provide factual information, prioritizing accuracy and
objectivity. Which option below correctly represents this
distinction?
Ano: 2025
Banca:
AMEOSC
Órgão:
Prefeitura de São Miguel do Oeste - SC
Prova:
AMEOSC - 2025 - Prefeitura de São Miguel do Oeste - SC - Professor de Língua Inglesa |
Q3643967
Inglês
When dealing with online texts, readers often face
challenges such as misinformation, biased arguments,
and lack of credible sources. Critical reading strategies
are essential for identifying the reliability of a text and
distinguishing between fact and opinion. In this context,
which element is explicitly required for a critical reader
when approaching online materials?
Ano: 2025
Banca:
AMEOSC
Órgão:
Prefeitura de São Miguel do Oeste - SC
Prova:
AMEOSC - 2025 - Prefeitura de São Miguel do Oeste - SC - Professor de Língua Inglesa |
Q3643966
Inglês
A student needs to write a formal complaint letter to a
company regarding a defective product. Which elements
are ESSENTIAL for this specific genre?
I.Formal salutation and closing.
II.Clear statement of the problem with specific details.
III.Creative narrative techniques to engage the reader.
IV.Professional tone throughout the document.
V.Specific request for resolution or action.
The appropriate combination is:
I.Formal salutation and closing.
II.Clear statement of the problem with specific details.
III.Creative narrative techniques to engage the reader.
IV.Professional tone throughout the document.
V.Specific request for resolution or action.
The appropriate combination is:
Ano: 2025
Banca:
AMEOSC
Órgão:
Prefeitura de São Miguel do Oeste - SC
Prova:
AMEOSC - 2025 - Prefeitura de São Miguel do Oeste - SC - Professor de Língua Inglesa |
Q3643965
Inglês
Cohesion in texts is achieved through linguistic elements
that connect sentences and ideas, such as conjunctions
and adverbial connectors. Consider the following
example:
"The company promised to reduce its carbon footprint. However, recent reports show an increase in emissions."
In this case, what is the function of the connector "however"?
"The company promised to reduce its carbon footprint. However, recent reports show an increase in emissions."
In this case, what is the function of the connector "however"?
Ano: 2025
Banca:
AMEOSC
Órgão:
Prefeitura de São Miguel do Oeste - SC
Prova:
AMEOSC - 2025 - Prefeitura de São Miguel do Oeste - SC - Professor de Língua Inglesa |
Q3643964
Inglês
Texto associado
O texto seguinte servirá de base para responder à questão.
Primate thumbs and brains evolved hand-in-hand
By University of Reading Tue, Aug 26, 2025
University of Reading - Longer thumbs mean bigger
brains, scientists have found − revealing how human
hands and minds evolved together. Researchers studied
94 different primate species, including fossils and living
animals, to understand how our ancestors developed
their abilities. They found that species with relatively
longer thumbs, which help with gripping small objects
precisely, consistently had larger brains. The research,
published today (Tuesday, 26 August) in
Communications Biology, provides the first direct
evidence that manual dexterity and brain evolution are
connected across the entire primate lineage, from lemurs
to humans. Humans and our extinct relatives boast both
extraordinarily long thumbs and exceptionally large
brains. However, the link remains strong across all
primates: when scientists removed human data from their
analysis, the connection between thumb length and brain
size remained.
Dr Joanna Baker, lead author from the University of
Reading, said: "We've always known that our big brains
and nimble fingers set us apart, but now we can see they
didn't evolve separately. As our ancestors got better at
picking up and manipulating objects, their brains had to
grow to handle these new skills. These abilities have
been fine-tuned through millions of years of brain
evolution."
Thumbs linked to thinking, not movement
The scientists made a surprising discovery about which
part of the brain grows alongside longer thumbs. They
expected longer thumbs to be linked to the cerebellum
because it is the region of the brain that controls
movement and coordination. Instead, longer thumbs
were connected to the neocortex (a complex layered
region comprising approximately half the volume of the
human brain), which processes sensory information and
handles cognition and consciousness.
It was a surprise that only one of the two major brain
regions they thought would be involved actually was. The
findings suggest that as primates developed better
manual skills for handling objects, their brains had to
grow to process and use these new abilities effectively −
but further work is needed to establish exactly how the
neocortex supports manipulative abilities.
https://popular-archaeology.com/article/primate-thumbs-and-brains-evol
ved-hand-in-hand/
In the passage, the word "dexterity" in the phrase
"manual dexterity and brain evolution" means:
Conheça nossos planos