Questões de Concurso Sobre pedagogia

Foram encontradas 153.263 questões

Q4393027 Pedagogia
A relação entre a escola e a família contribui para o acompanhamento do desenvolvimento educacional do estudante público-alvo da Educação Especial. Considerando as responsabilidades predominantes de cada parte nessa relação, associe a coluna I à coluna II.

Coluna I
1.Escola.
2.Família.

Coluna II
(__)Sistematização das informações relativas ao desenvolvimento educacional do estudante, acompanhada da apresentação das possibilidades institucionais de apoio.
(__)Análise das orientações recebidas e participação nas decisões referentes aos recursos e atendimentos considerados necessários.
(__)Organização de oportunidades coletivas de diálogo que favoreçam a reflexão sobre dificuldades, possibilidades de enfrentamento e formas de participação.
(__)Comunicação de elementos observados em diferentes situações da vida do estudante que possam contribuir para a compreensão de suas necessidades.
(__)Articulação das informações compartilhadas com as estratégias pedagógicas e com os encaminhamentos pertinentes ao processo de inclusão.

Assinale a alternativa que apresenta a sequência correta, de cima para baixo.
Alternativas
Q4393025 Pedagogia
A avaliação mediadora fundamenta-se em princípios coerentes com uma perspectiva educacional inclusiva. Analise o excerto a seguir:

As tarefas são elementos essenciais para a observação das hipóteses construídas pelos alunos ao longo do processo. Por meio delas, professores de todos os graus de ensino poderão estabelecer o diálogo com os educandos, no sentido de debruçar-se sobre sua produção de conhecimento para compreender em que momento se encontram, qual a dimensão do seu entendimento. Preocupam-me entendimentos sobre uma prática avaliativa inovadora que abandone a realização de tarefas pelos alunos em qualquer grau de ensino. É importante que se respeite o saber elaborado pelo aluno, espontâneo, partindo de ações desencadeadoras de reflexão sobre tal saber, desafiando-o a evoluir, encontrar novas e diferentes soluções às tarefas sucessivamente apresentadas pelo professor. 

Fonte: HOFFMANN, Jussara. Avaliação mediadora: uma prática em construção da pré-escola à universidade. 32. ed. Porto Alegre: Mediação, 2012.

Ao destacar a observação das hipóteses construídas pelos estudantes e o diálogo do professor com sua produção de conhecimento, o excerto relaciona-se, principalmente, ao princípio de:
Alternativas
Q4393024 Pedagogia
As Salas de Recursos Multifuncionais (SRM) são espaços escolares destinados à realização do Atendimento Educacional Especializado (AEE). Considerando a organização da SRM no AEE, analise os itens a seguir:

I.A atuação desenvolvida nesses espaços deve subsidiar os estudantes na apropriação do currículo e na ampliação de suas condições de participação na vida escolar.
II.O emprego dos materiais deve ter como critério central o pertencimento ao público-alvo da Educação Especial, reservando a esse grupo as possibilidades de enriquecimento das formas de aprendizagem.
III.A organização do atendimento pressupõe o desenvolvimento de estratégias de aprendizagem vinculadas a um fazer pedagógico que favoreça a construção de conhecimentos pelos estudantes.

É correto o que se afirma em:
Alternativas
Q4393023 Pedagogia
O art. 24 da Lei Federal nº 9.394/1996, Lei de Diretrizes e Bases da Educação Nacional (LDB), estabelece regras comuns para a organização dos ensinos fundamental e médio. No que se refere aos critérios de verificação do rendimento escolar, analise as afirmativas:

I.Admite-se a aceleração de estudos para estudantes que demonstrem aprendizagem superior à prevista para a etapa escolar em que se encontram.
II.Admite-se o avanço nos cursos e nas séries mediante a verificação da aprendizagem do estudante.
III.Podem ser aproveitados os estudos anteriormente concluídos com êxito.

É CORRETO o que se afirma em:
Alternativas
Q4393022 Pedagogia
Uma escola identifica que determinado estudante apresenta necessidades educacionais que demandam uma análise mais aprofundada. Para subsidiar a tomada de decisões quanto ao atendimento necessário, a equipe gestora avalia formas de conduzir esse processo com base na colaboração institucional. Considerando essa situação, analise as asserções a seguir e a relação estabelecida entre elas:

I.A avaliação do estudante no processo de ensino e aprendizagem deve articular, com o devido assessoramento técnico, a experiência do corpo docente, dos diretores, coordenadores, orientadores e supervisores educacionais.

PORQUE

II.Compete ao setor responsável pela Educação Especial validar as decisões formuladas pelos diferentes profissionais envolvidos, conferindo a aprovação final às medidas educacionais propostas.

A respeito dessas asserções, assinale a alternativa correta.
Alternativas
Q4393021 Pedagogia
A Comunicação Aumentativa e Alternativa (CAA) compreende símbolos que podem ser classificados conforme os meios empregados pelo usuário na produção das mensagens. Considerando essa classificação, associe a coluna I à coluna II.

Coluna I
1.Símbolos sem apoio.
2.Símbolos com apoio.
3.Símbolos combinados.

Coluna II
(__)Utilização de fotografias, pictogramas, objetos reais ou miniaturas como elementos externos para a produção da mensagem.
(__)Emprego articulado de sinais manuais e símbolos gráficos durante uma mesma situação comunicativa.
(__)Produção da mensagem por meio de gestos, expressões faciais, sinais manuais ou vocalizações, sem o emprego de recursos externos ao corpo do usuário.

Assinale a alternativa que apresenta a sequência correta, de cima para baixo.
Alternativas
Q4393020 Pedagogia
A documentação pedagógica do estudante público da Educação Especial não se restringe ao registro de informações nem ao cumprimento de uma exigência administrativa. Ela pode fortalecer as práticas inclusivas ao valorizar a singularidade do estudante, suas múltiplas linguagens e seus modos próprios de aprender. Assim, documentar significa reconhecê-lo como sujeito de direitos e reafirmar a responsabilidade da escola de organizar condições para sua aprendizagem e participação.

Fonte: PLETSCH, Márcia Denise et al. Documentação do AEE na escola inclusiva: estudo de caso, PAEE e PEI. Fortaleza: Imprensa Universitária, 2026.

Considere as ações relacionadas à elaboração e à avaliação da documentação pedagógica, apresentadas a seguir fora de sua ordem de desenvolvimento:

1.Revisão contínua das práticas educativas desenvolvidas.
2.Reconhecimento das potencialidades apresentadas pelo estudante.
3.Definição de apoios, recursos e estratégias pedagógicas para a acessibilidade curricular.
4.Identificação das barreiras que interferem na aprendizagem e na participação.

Assinale a alternativa que apresenta a sequência adequada dessas ações no processo de elaboração, acompanhamento e revisão do Plano de Atendimento Educacional Especializado (PAEE) e do Plano de Ensino Individualizado (PEI).
Alternativas
Q4393018 Pedagogia
Os critérios diagnósticos do Transtorno do Espectro Autista (TEA) abrangem déficits na comunicação e na interação social, bem como padrões restritos e repetitivos de comportamentos, interesses ou atividades. Além desses domínios, são estabelecidos três níveis de gravidade, definidos conforme a necessidade de suporte e o impacto das características apresentadas no funcionamento do indivíduo. Considerando esses aspectos e suas implicações para a intervenção pedagógica, analise os itens a seguir:

I.A definição das estratégias pedagógicas deve considerar as manifestações apresentadas nos dois domínios e as necessidades individuais do estudante, uma vez que a classificação no mesmo nível de suporte não determina, por si só, intervenções idênticas.
II.O estudante classificado no nível 1 apresenta dificuldades nas situações de maior complexidade, razão pela qual pode dispensar estratégias específicas de mediação no contexto escolar.
III.Para o estudante do nível 2, a antecipação de mudanças, a organização de rotinas e a mediação das interações podem reduzir os impactos da inflexibilidade comportamental e das dificuldades de comunicação social.
IV.No nível 3, a necessidade de apoio muito substancial demanda intervenções mais intensivas e sistemáticas, sem que isso implique abandonar objetivos relacionados à comunicação, à participação e à autonomia do estudante.

É correto o que se afirma em:
Alternativas
Q4393016 Pedagogia
O Projeto Político-Pedagógico (PPP) é responsável por unificar as atividades e os procedimentos realizados durante determinado período, sendo construído e vivenciado por todos os envolvidos no processo educativo. É considerado, portanto, um dos principais documentos norteadores do trabalho pedagógico de uma instituição de ensino.

Na construção de um projeto escolar, são registrados o planejamento, os objetivos definidos, as ações e os métodos necessários para alcançá-los, visando a um processo de escolarização que atenda a todos os estudantes. Nesse sentido, um dos desafios consiste em manter o PPP como referência para as ações cotidianas e transformá-lo em um mecanismo efetivo de participação. 

Fonte: ALVES, Marlisson Jacinto Cintra et al. Diálogo sobre projeto político-pedagógico na comunidade escolar. In: ENCONTRO DE PESQUISA EDUCACIONAL EM PERNAMBUCO, 8., 2021, on-line. Anais [...]. Campina Grande: Realize Editora, 2021.

Considerando essa finalidade, assinale a alternativa que apresenta uma medida coerente com a construção participativa do PPP.
Alternativas
Q4393015 Pedagogia
Sobre os estudantes com altas habilidades/superdotação, analise as asserções a seguir e a relação proposta entre elas:

I.Demonstram potencial elevado em uma ou mais das seguintes áreas, isoladas ou combinadas: intelectual, acadêmica, liderança, psicomotricidade e artes.

PORQUE

II.Também apresentam grande criatividade, envolvimento na aprendizagem e realização de tarefas, independentemente de estas corresponderem às suas áreas de interesse.

A respeito dessas asserções, assinale a alternativa correta. 
Alternativas
Q4393014 Pedagogia
O Desenho Universal para a Aprendizagem (DUA) amplia a compreensão de acesso educacional para além da dimensão física. Nessa perspectiva, o principal obstáculo à promoção da aprendizagem encontra-se nos currículos __________, organizados segundo a lógica de __________, que produzem barreiras __________ e afetam particularmente os estudantes situados __________ da variabilidade educacional.

Assinale a alternativa que preenche corretamente as lacunas. 
Alternativas
Q4393013 Pedagogia
O Soroban originou-se do ábaco, instrumento de cálculo utilizado pelos povos orientais desde antes da era cristã. Sua estrutura e metodologia favorecem a compreensão do valor posicional dos números, o desenvolvimento do cálculo mental, a concentração, a agilidade e a autonomia. Considerando as características estruturais desse instrumento, associe a coluna I à coluna II.

Coluna I
1.Travessa ou régua longitudinal.
2.Eixos ou hastes verticais.
3.Contas do Céu.
4.Pontos em relevo.

Coluna II
(__)Representam as ordens numéricas e permitem o deslizamento das contas.
(__)Divide o instrumento em partes superior e inferior, separando as contas de valor 5 das contas de valor 1.
(__)Correspondem a uma conta localizada na parte superior de cada eixo, com valor numérico 5.
(__)Indicam, ao longo da régua, a separação das classes numéricas.

Assinale a alternativa que apresenta a sequência correta, de cima para baixo.
Alternativas
Q4392995 Pedagogia
The National Curriculum Guidelines for Basic Education establish principles that affect curriculum organization, school planning and the formulation of the political-pedagogical project.

Judge the statements below as True (T) or False (F):

(__)The Guidelines emphasize the subjects who give life to the curriculum and to the school when discussing the common national educational foundation.
(__)The political-pedagogical project is conceived essentially as an administrative document whose main purpose is to formalize decisions already established by the education system.
(__)The Guidelines associate education with citizenship, human dignity, pluralism, diversity, justice and other principles related to a broader project of society.
(__)The Guidelines are intended to orient public education systems but do not extend their general educational principles to private Basic Education institutions.

The correct sequence, from top to bottom, is:
Alternativas
Q4392994 Pedagogia
Read the study case:

A teacher and a Geography colleague plan a bilingual sequence on urban water management. Students must understand geographic concepts, interpret maps, compare municipal data and communicate explanations in English. The English teacher provides language scaffolds for comparison, cause and consequence without reducing the academic complexity of the Geography content.

Which interpretation of the sequence is most consistent with Content and Language Integrated Learning (CLIL)? 
Alternativas
Q4392992 Pedagogia
A public school establishes that students with low academic achievement may participate in recovery activities only after the final examination. An English teacher questions whether this procedure is compatible with the general principles of student assessment and learning recovery in Basic Education.

Considering the rules applicable to assessment of school performance and recovery of students with low achievement, select the correct alternative. 
Alternativas
Q4392990 Pedagogia
Read the study case:

At the end of a term, an English teacher notices that some entries in the class diary were completed retrospectively from memory, while attendance records in the school system differ from handwritten notes. The teacher also discovers that assessment procedures recorded in the diary do not correspond to the criteria established in the school's pedagogical proposal.

Considering the relationship among teaching records, attendance control and institutional pedagogical planning, select the correct course of action.
Alternativas
Q4392985 Pedagogia
O texto seguinte servirá de base para responder à questão.


A leader in the study of longevity is returning to UCLA Health


Renowned geroscientist and computational biologist Steve Horvath, PhD, is returning as a professor in the David Geffen School of Medicine at UCLA on July 1, after 4 1/2 years in the biotech industry. Previously, he was a full-time professor of Human Genetics and Biostatistics at UCLA for 22 years.

Geroscience is the modern term for the biology of aging. Dr. Horvath, who was born in Germany, is internationally known for his research into the aging process and, in particular, epigenetics, how the environment influences our genes, affecting a person's longevity.

His groundbreaking research, which he began at UCLA in 2011, looked at the "epigenetic age" of more than 13,000 DNA samples of people from the U.S. and Europe, determined from the chemical modifications of their DNA (also called DNA methylation).

People whose epigenetic age was higher than their chronological age were shown to be at an increased risk of death from all causes. From this, Dr. Horvath developed the "epigenetic clock," a way of measuring biological aging and mortality risk.

"The universal mammalian methylation clock was really a UCLA triumph — a true team effort," said Dr. Horvath, who received the 2026 Luminary Award at the Precision Medicine World Conference. That project, part of the international Mammalian Methylation Consortium that Dr. Horvath led, drew on collaborators across UCLA, including Jason Ernst, PhD; William Yang, MD, PhD; Ebru Erbay, MD, PhD; Karen Sears, PhD; and Ren Larison, PhD.

Aging is a growing field of study and the Division of Geriatrics is a research leader.

"Aging happens at the cellular level — every tissue in the human body shows signs of aging," explained Arun S. Karlamangla, MD, PhD, chief of the UCLA Division of Geriatrics. "The epigenetic profile is affected by stresses in life. As we age, these stresses change DNA functionality. Dr. Horvath's research showed that these changes can be quantified and used to predict a person's lifespan."

None of us has control over the DNA we're born with, but we do have some control over how long we live.

"The epigenetic clock is one window into biological aging, but it doesn't capture everything, and plenty of well-established factors influence how long and how well a person lives," said Dr. Horvath. "The strongest evidence is for the basics: not smoking, maintaining a healthy weight, a sensible diet, regular physical activity and good sleep."

Dr. Horvath has run the test on himself and by the epigenetic clock, he is about three years younger than his chronological age of 58.

New medications also show promise for improving longevity, he said. "There's active research interest in newer GLP-1 receptor agonists — e.g., the Ozempic/Wegovy class — which are reshaping how we think about metabolic health," said Dr. Horvath, adding that the same is true for anti-inflammatory and antifibrotic drugs.

Dr. Horvath's epigenetic clocks have become standard tools across aging research, used by teams worldwide to test what actually changes biological aging. 

They have been applied in the randomized DO-HEALTH trial, where omega-3, vitamin D and exercise modestly slowed epigenetic aging in adults older than 70; in the Women's Health Initiative, where faster epigenetic aging tracked with later cognitive impairment and dementia; and in studies of cardiovascular disease and mortality. This kind of population-level application aligns closely with the Division of Geriatrics' emphasis on healthy, independent life expectancy.

Dr. Horvath's research has also shown that the cells of different organs age at different rates. For instance, the liver ages faster than other organs, he said, particularly in the case of people with obesity.

Another discovery was that the blood and brain tissues of human males age faster than those of females, which might be the reason women live longer on average than men across all cultures and countries.

Leading in aging research

The study of aging at the UCLA Division of Geriatrics focuses on understanding the epidemiology of age-related conditions such as frailty, cognitive impairment and dementia, and improving the delivery of compassionate, comprehensive care to older adults.

Dr. Horvath's return to UCLA will bolster the department's role in aging research by translating his cellular research to clinical trials, said Dr. Karlamangla.

"We want to be pioneers in all three aspects: cellular research, clinical and population-level research, and health services and implementation research," Dr. Karlamangla said. "We are one of the pioneers in clinical innovation for the delivery of healthcare to older adults," he said, an approach that is called bench to bedside.

Life expectancy is important, but even more important is good health, which is necessary for independence, Dr. Karlamangla emphasized. This is referred to as healthy life expectancy, or independent life expectancy.

New work at UCLA

Along with serving as a professor, Dr. Horvath will return to UCLA Health as director of aging biology research in the Department of Medicine, working across 11 divisions. In this way, he will work directly with doctors to apply aging research to their patients. The move into the Department of Medicine is deliberate: his focus now is translating discoveries from aging biology into care for patients.
"What I'm most looking forward to in returning to UCLA is the people and the collaborative environment," said Dr. Horvath. "UCLA has remarkable strength across medicine, computational biology, stem cell biology, and the basic science of complex diseases, and being back in that setting with former colleagues and future students is what excites me most.

"It feels like the right place to do the next phase of this work: helping to translate findings from aging biology into the clinic."


https://www.uclahealth.org/news/article/leader-study-longevity-returning -ucla-health 
Read the study case:

A teacher in a state school plans a sequence based on the UCLA Health article. The stated objective is for students to distinguish scientific findings from tentative claims and produce a concise evidence-based summary. The teacher intends to integrate a collaborative digital platform into the sequence.

Considering coherence among objectives, teaching activities, assessment evidence and the pedagogical use of digital technology, select the correct alternative. 
Alternativas
Q4392981 Pedagogia
O texto seguinte servirá de base para responder à questão.


A leader in the study of longevity is returning to UCLA Health


Renowned geroscientist and computational biologist Steve Horvath, PhD, is returning as a professor in the David Geffen School of Medicine at UCLA on July 1, after 4 1/2 years in the biotech industry. Previously, he was a full-time professor of Human Genetics and Biostatistics at UCLA for 22 years.

Geroscience is the modern term for the biology of aging. Dr. Horvath, who was born in Germany, is internationally known for his research into the aging process and, in particular, epigenetics, how the environment influences our genes, affecting a person's longevity.

His groundbreaking research, which he began at UCLA in 2011, looked at the "epigenetic age" of more than 13,000 DNA samples of people from the U.S. and Europe, determined from the chemical modifications of their DNA (also called DNA methylation).

People whose epigenetic age was higher than their chronological age were shown to be at an increased risk of death from all causes. From this, Dr. Horvath developed the "epigenetic clock," a way of measuring biological aging and mortality risk.

"The universal mammalian methylation clock was really a UCLA triumph — a true team effort," said Dr. Horvath, who received the 2026 Luminary Award at the Precision Medicine World Conference. That project, part of the international Mammalian Methylation Consortium that Dr. Horvath led, drew on collaborators across UCLA, including Jason Ernst, PhD; William Yang, MD, PhD; Ebru Erbay, MD, PhD; Karen Sears, PhD; and Ren Larison, PhD.

Aging is a growing field of study and the Division of Geriatrics is a research leader.

"Aging happens at the cellular level — every tissue in the human body shows signs of aging," explained Arun S. Karlamangla, MD, PhD, chief of the UCLA Division of Geriatrics. "The epigenetic profile is affected by stresses in life. As we age, these stresses change DNA functionality. Dr. Horvath's research showed that these changes can be quantified and used to predict a person's lifespan."

None of us has control over the DNA we're born with, but we do have some control over how long we live.

"The epigenetic clock is one window into biological aging, but it doesn't capture everything, and plenty of well-established factors influence how long and how well a person lives," said Dr. Horvath. "The strongest evidence is for the basics: not smoking, maintaining a healthy weight, a sensible diet, regular physical activity and good sleep."

Dr. Horvath has run the test on himself and by the epigenetic clock, he is about three years younger than his chronological age of 58.

New medications also show promise for improving longevity, he said. "There's active research interest in newer GLP-1 receptor agonists — e.g., the Ozempic/Wegovy class — which are reshaping how we think about metabolic health," said Dr. Horvath, adding that the same is true for anti-inflammatory and antifibrotic drugs.

Dr. Horvath's epigenetic clocks have become standard tools across aging research, used by teams worldwide to test what actually changes biological aging. 

They have been applied in the randomized DO-HEALTH trial, where omega-3, vitamin D and exercise modestly slowed epigenetic aging in adults older than 70; in the Women's Health Initiative, where faster epigenetic aging tracked with later cognitive impairment and dementia; and in studies of cardiovascular disease and mortality. This kind of population-level application aligns closely with the Division of Geriatrics' emphasis on healthy, independent life expectancy.

Dr. Horvath's research has also shown that the cells of different organs age at different rates. For instance, the liver ages faster than other organs, he said, particularly in the case of people with obesity.

Another discovery was that the blood and brain tissues of human males age faster than those of females, which might be the reason women live longer on average than men across all cultures and countries.

Leading in aging research

The study of aging at the UCLA Division of Geriatrics focuses on understanding the epidemiology of age-related conditions such as frailty, cognitive impairment and dementia, and improving the delivery of compassionate, comprehensive care to older adults.

Dr. Horvath's return to UCLA will bolster the department's role in aging research by translating his cellular research to clinical trials, said Dr. Karlamangla.

"We want to be pioneers in all three aspects: cellular research, clinical and population-level research, and health services and implementation research," Dr. Karlamangla said. "We are one of the pioneers in clinical innovation for the delivery of healthcare to older adults," he said, an approach that is called bench to bedside.

Life expectancy is important, but even more important is good health, which is necessary for independence, Dr. Karlamangla emphasized. This is referred to as healthy life expectancy, or independent life expectancy.

New work at UCLA

Along with serving as a professor, Dr. Horvath will return to UCLA Health as director of aging biology research in the Department of Medicine, working across 11 divisions. In this way, he will work directly with doctors to apply aging research to their patients. The move into the Department of Medicine is deliberate: his focus now is translating discoveries from aging biology into care for patients.
"What I'm most looking forward to in returning to UCLA is the people and the collaborative environment," said Dr. Horvath. "UCLA has remarkable strength across medicine, computational biology, stem cell biology, and the basic science of complex diseases, and being back in that setting with former colleagues and future students is what excites me most.

"It feels like the right place to do the next phase of this work: helping to translate findings from aging biology into the clinic."


https://www.uclahealth.org/news/article/leader-study-longevity-returning -ucla-health 
Read the study case:

An English teacher in a public secondary school intends to use the UCLA Health article through Task-Based Language Teaching. The students already possess enough linguistic support to work with the text. The teacher wants the lesson to retain a genuine communicative outcome while also creating opportunities for subsequent attention to language.

Considering TBLT (Task-Based Language Teaching) principles, select the correct alternative.
Alternativas
Q4392980 Pedagogia
O texto seguinte servirá de base para responder à questão.


A leader in the study of longevity is returning to UCLA Health


Renowned geroscientist and computational biologist Steve Horvath, PhD, is returning as a professor in the David Geffen School of Medicine at UCLA on July 1, after 4 1/2 years in the biotech industry. Previously, he was a full-time professor of Human Genetics and Biostatistics at UCLA for 22 years.

Geroscience is the modern term for the biology of aging. Dr. Horvath, who was born in Germany, is internationally known for his research into the aging process and, in particular, epigenetics, how the environment influences our genes, affecting a person's longevity.

His groundbreaking research, which he began at UCLA in 2011, looked at the "epigenetic age" of more than 13,000 DNA samples of people from the U.S. and Europe, determined from the chemical modifications of their DNA (also called DNA methylation).

People whose epigenetic age was higher than their chronological age were shown to be at an increased risk of death from all causes. From this, Dr. Horvath developed the "epigenetic clock," a way of measuring biological aging and mortality risk.

"The universal mammalian methylation clock was really a UCLA triumph — a true team effort," said Dr. Horvath, who received the 2026 Luminary Award at the Precision Medicine World Conference. That project, part of the international Mammalian Methylation Consortium that Dr. Horvath led, drew on collaborators across UCLA, including Jason Ernst, PhD; William Yang, MD, PhD; Ebru Erbay, MD, PhD; Karen Sears, PhD; and Ren Larison, PhD.

Aging is a growing field of study and the Division of Geriatrics is a research leader.

"Aging happens at the cellular level — every tissue in the human body shows signs of aging," explained Arun S. Karlamangla, MD, PhD, chief of the UCLA Division of Geriatrics. "The epigenetic profile is affected by stresses in life. As we age, these stresses change DNA functionality. Dr. Horvath's research showed that these changes can be quantified and used to predict a person's lifespan."

None of us has control over the DNA we're born with, but we do have some control over how long we live.

"The epigenetic clock is one window into biological aging, but it doesn't capture everything, and plenty of well-established factors influence how long and how well a person lives," said Dr. Horvath. "The strongest evidence is for the basics: not smoking, maintaining a healthy weight, a sensible diet, regular physical activity and good sleep."

Dr. Horvath has run the test on himself and by the epigenetic clock, he is about three years younger than his chronological age of 58.

New medications also show promise for improving longevity, he said. "There's active research interest in newer GLP-1 receptor agonists — e.g., the Ozempic/Wegovy class — which are reshaping how we think about metabolic health," said Dr. Horvath, adding that the same is true for anti-inflammatory and antifibrotic drugs.

Dr. Horvath's epigenetic clocks have become standard tools across aging research, used by teams worldwide to test what actually changes biological aging. 

They have been applied in the randomized DO-HEALTH trial, where omega-3, vitamin D and exercise modestly slowed epigenetic aging in adults older than 70; in the Women's Health Initiative, where faster epigenetic aging tracked with later cognitive impairment and dementia; and in studies of cardiovascular disease and mortality. This kind of population-level application aligns closely with the Division of Geriatrics' emphasis on healthy, independent life expectancy.

Dr. Horvath's research has also shown that the cells of different organs age at different rates. For instance, the liver ages faster than other organs, he said, particularly in the case of people with obesity.

Another discovery was that the blood and brain tissues of human males age faster than those of females, which might be the reason women live longer on average than men across all cultures and countries.

Leading in aging research

The study of aging at the UCLA Division of Geriatrics focuses on understanding the epidemiology of age-related conditions such as frailty, cognitive impairment and dementia, and improving the delivery of compassionate, comprehensive care to older adults.

Dr. Horvath's return to UCLA will bolster the department's role in aging research by translating his cellular research to clinical trials, said Dr. Karlamangla.

"We want to be pioneers in all three aspects: cellular research, clinical and population-level research, and health services and implementation research," Dr. Karlamangla said. "We are one of the pioneers in clinical innovation for the delivery of healthcare to older adults," he said, an approach that is called bench to bedside.

Life expectancy is important, but even more important is good health, which is necessary for independence, Dr. Karlamangla emphasized. This is referred to as healthy life expectancy, or independent life expectancy.

New work at UCLA

Along with serving as a professor, Dr. Horvath will return to UCLA Health as director of aging biology research in the Department of Medicine, working across 11 divisions. In this way, he will work directly with doctors to apply aging research to their patients. The move into the Department of Medicine is deliberate: his focus now is translating discoveries from aging biology into care for patients.
"What I'm most looking forward to in returning to UCLA is the people and the collaborative environment," said Dr. Horvath. "UCLA has remarkable strength across medicine, computational biology, stem cell biology, and the basic science of complex diseases, and being back in that setting with former colleagues and future students is what excites me most.

"It feels like the right place to do the next phase of this work: helping to translate findings from aging biology into the clinic."


https://www.uclahealth.org/news/article/leader-study-longevity-returning -ucla-health 
Read the study case:

After students read the article, a public-school teacher asks them to explain the concept of the "epigenetic clock" to a non-specialist audience. Before the activity, the class receives criteria concerning accuracy, clarity, use of evidence and linguistic appropriateness. The teacher then analyses the first versions, provides criterion-based feedback and allows students to revise their texts before the final submission.

In this situation, what clearly characterizes the assessment as formative?
Alternativas
Q4392679 Pedagogia
O Plano Nacional de Educação, estabelecido por lei em consonância com as diretrizes constitucionais federais, caracteriza‑se por
Alternativas
Respostas
1101: B
1102: A
1103: D
1104: C
1105: D
1106: C
1107: B
1108: A
1109: C
1110: A
1111: B
1112: A
1113: A
1114: D
1115: D
1116: B
1117: B
1118: A
1119: D
1120: C